Research
Metabolism-epigenetic interactions in Drosophila : P.Jouandin

Activities

Using Drosophila, we explore metabolic/epigenetic regulation of Innate immune recognition to better address cancers and autoimmune diseases.

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Main Publications

Liu G, Jouandin P, Bahng R, Perrimon N, Sabatini D An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathway. Nature Communications. 2024;15(1):2517. doi:10.1038/s41467-024-46680-3

Gu X, Jouandin P, Lalgudi P, Binari R, Valenstein M, Reid M, Allen A, Kamitaki N, Locasale J, Perrimon N, Sabatini D Sestrin mediates detection of and adaptation to low-leucine diets in Drosophila. Nature. 2022;608(7921):209-216. doi:10.1038/s41586-022-04960-2

Jouandin P, Marelja Z, Shih Y-H, Parkhitko A, Dambowsky M, Asara J, Nemazanyy I, Dibble C, Simons M, Perrimon N Lysosomal cystine mobilization shapes the response of TORC1 and tissue growth to fasting. Science. 2022;375(6582):eabc4203. doi:10.1126/science.abc4203

Parkhitko A, Jouandin P, Mohr S, Perrimon N Methionine metabolism and methyltransferases in the regulation of aging and lifespan extension across species. Aging Cell. 2019;18(6):e13034. doi:10.1111/acel.13034

Ghiglione C, Jouandin P, Noselli S The Drosophila insulin pathway controls Profilin expression and dynamic actin-rich protrusions during collective cell migration. Development. 2018;145(14):dev161117. doi:10.1242/dev.161117


Team

Team Leader :
Patrick Jouandin

 

Institut de Recherche en
Cancérologie de Montpellier
Campus Val d’Aurelle

34298 Montpellier cedex 5

Tél. 33 (0)4 11 28 31 13
patrick.jouandin@inserm.fr


© Institut de Recherche en Cancérologie de Montpellier - 2011 - Tous droits réservés - Mentions légales - Connexion - Conception : ID Alizés