
Institute for Radiation Sciences, Osaka University, Japan
Professor Kazuya Kabayama leads the Laboratory for Radiation Chemical Biology at Osaka University, where his research bridges chemistry, cellular biology, and nuclear medicine. His primary focus is on developing innovative treatments in radiotherapy, particularly targeted alpha therapy (TAT) using astatine-211 (211At), a promising alpha-emitting radionuclide for the treatment of resistant cancers. Professor Kabayama has contributed significantly to the design and synthesis of 211At-labeled compounds aimed at first-in-human clinical trials. He has also participated in studies exploring 211At-labeled gold nanoparticles, demonstrating their potent antitumor effects. His work plays a key role in advancing the clinical translation of alpha-based radiopharmaceuticals. In parallel, his research investigates molecular interactions involving lipids and glycans, especially in the context of innate immunity and diseases such as cancer and diabetes. His team develops real-time cellular imaging tools to analyze the dynamics of glycolipids and multivalent glycan-receptor interactions at the membrane level. Through a highly interdisciplinary approach combining organic chemistry, radiobiology, and molecular imaging, Professor Kabayama contributes to the advancement of targeted therapies and the fundamental understanding of complex disease mechanisms. His work positions him at the forefront of innovation in both therapeutic and diagnostic strategies in nuclear medicine.
host : Jean-Pierre POUGET (IRCM)
Institut de Génomique Fonctionnelle de Lyon (IGFL), UMR 5242 CNRS / E.N.S. de Lyon (France)
hôte : Alexandre DJIANE et Jennifer FALCONI (IRCM-Inserm)
Department of Translational Research and New Technologies in Medicine, University of Pisa, Italy.
hôte : Andredi Turtoi (IRCM)
DEPARTMENT OF BIOSYSTEMS SCIENCE
Lab of Cell Fate Dynamics and Therapeutics
Kyoto University, Japan
host : Andrei Turtoï (IRCM)