Research
Functional screening and targeting in cancer : P. Martineau

publications

Leenhardt F, Ares P, Nicolai A, Corbinais C, Viala M, Jouvet F, Pinguet F [Early non-compliance with oral anticancer drugs, a clinical pharmacy as key issue in onco-senology]. Therapie. 2025-06-09. doi:10.1016/j.therap.2025.06.001

Falvo P, Multrier C, Lombardi D, Bertolini F, Martineau P, Robert B, Cartron G, Villalba M The Arming of Natural Killer Cells With Fc-Engineered Monoclonal Antibodies Confers Specificity Against Tumor B Cells. 2025;6(7):e70242. doi:10.1002/mco2.70242

Fauvre A, Ursino C, Culerier E, Milazzo L-A, Jeanson L, Marchive C, Andrade A, Combes E, Atis S, Michaud H-A, Khellaf L, Corbeau I, Tosi D, Bonnefoy N, Sgarbura O, Gongora C, Faget J Oxaliplatin, ATR inhibitor and anti-PD-1 antibody combination therapy controls colon carcinoma growth, induces local and systemic changes in the immune compartment, and protects against tumor rechallenge in mice. J Immunother Cancer. 2025;13(3):e010791. doi:10.1136/jitc-2024-010791

Abba Moussa D, Vazquez M, Chable-Bessia C, Roux-Portalez V, Tamagnini E, Pedotti M, Simonelli L, Ngo G, Souchard M, Chentouf M, Gros N, Marsile-Medun S, Dinter H, Pugnière M, Martineau P, Varani L, Juan M, Calderon H, Naranjo-Gomez M, Pelegrin M Discovery of a pan anti-SARS-CoV-2 monoclonal antibody with highly efficient infected cell killing capacity for novel immunotherapeutic approaches. Emerg Microbes Infect. 2025;14(1):2432345. doi:10.1080/22221751.2024.2432345

Marquant A, Berthelot J, Bich C, Elfekih Z, Simon L, Robin B, Chopineau J, Wang D, Emerson S, Wang A, Benedetti C, Langlois S, Guglielmi L, Martineau P, Aubert-Pouëssel A, Morille M Control of Physical and Biochemical Parameters Influencing Exogeneous Cargo Protein Association to Extracellular Vesicles Using Lipid Anchors Enables High Loading and Effective Intracellular Delivery. J Extracell Biol. 2025;4(5):e70048. doi:10.1002/jex2.70048

Quénet F, Carrère S, Sgarbura O [Contribution of intraperitoneal chemotherapy in the treatment of colorectal peritoneal carcinoma. HIPEC, PIPAC, state of the art and future directions]. Bull Cancer. 2024;111(3):285-290. doi:10.1016/j.bulcan.2023.10.006

Aubert M, Mege D, Ezzedine W, Pocard M, Quenet F, Wernert R, Glehen O, Pirro N Impact of obesity after cytoreductive surgery and intraperitoneal hyperthermic chemotherapy for rare peritoneal malignancies: Paradox of obesity or poor prognostic factor?. Eur J Surg Oncol. 2024;50(9):108507. doi:10.1016/j.ejso.2024.108507

Mairaville C, Broyon M, Maurel M, Chentouf M, Chiavarina B, Turtoi A, Pirot N, Martineau P Identification of monoclonal antibodies from naive antibody phage-display libraries for protein detection in formalin-fixed paraffin-embedded tissues. J Immunol Methods. 2024;532. doi:10.1016/j.jim.2024.113730

Fisher O, Brown C, Esquivel J, Larsen S, Liauw W, Alzahrani N, Morris D, Kepenekian V, Sourrouille I, Tuech J-J, Ceribelli C, Sgarbura O, Alhosni M, Glehen O, Cashin P Hyperthermic intraperitoneal chemotherapy in colorectal cancer. BJS Open. 2024;8(3):zrae017. doi:10.1093/bjsopen/zrae017

Classe J-M, Meeus P, Hudry D, Wernert R, Marchal F, Houvenaeghel G, Bats A-S, Lecuru F, Ferron G, Brigand C, Berton D, Gladieff L, Joly F, Ray-Coquard I, Durand-Fontanier S, Liberale G, Pocard M, Georgeac C, Gouy S, Guilloit J-M, Guyon F, Costan C, Rousselet J-M, de Guerké L, Bakrin N, Brument E, Martin E, Asselain B, Campion L, Glehen O Hyperthermic intraperitoneal chemotherapy for recurrent ovarian cancer (CHIPOR): a randomised, open-label, phase 3 trial. Lancet Oncol. 2024;25(12):1551-1562. doi:10.1016/S1470-2045(24)00531-X

Rigal E, Courot H, Multrier C, Zemiti S, Lambour J, Pugnière M, de Toledo M, Bossis G, Cartron G, Robert B, Martineau P, Fauvel B, Presumey J, Villalba M Generation of non-genetically modified, CAR-like, NK cells. J Immunother Cancer. 2024;12(7):e009070. doi:10.1136/jitc-2024-009070

Trecourt A, Bakrin N, Glehen O, Gertych W, Villeneuve L, Isaac S, Benzerdjeb N, Fontaine J, Genestie C, Dartigues P, Leroux A, Odin C, Khellaf L, Svrcek M, Thierry S, Augros M, Omar A, Devouassoux-Shisheboran M, Kepenekian V Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy to Treat Pseudomyxoma Peritonei of Ovarian Origin: A Retrospective French RENAPE Group Study. Ann Surg Oncol. 2024;31(5):3325-3338. doi:10.1245/s10434-023-14850-0

Trecourt A, Bakrin N, Glehen O, Gertych W, Villeneuve L, Isaac S, Benzerdjeb N, Fontaine J, Genestie C, Dartigues P, Leroux A, Odin C, Khellaf L, Svrcek M, Thierry S, Augros M, Omar A, Devouassoux-Shisheboran M, Kepenekian V ASO Visual Abstract: Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy to Treat Pseudomyxoma Peritonei of Ovarian Origin: A Retrospective French RENAPE Group Study. Ann Surg Oncol. 2024-02-09. doi:10.1245/s10434-024-14925-6

Desroys du Roure P, Lajoie L, Mallavialle A, Alcaraz L, Mansouri H, Fenou L, Garambois V, Rubio L, David T, Coenon L, Boissière-Michot F, Chateau M-C, Ngo G, Jarlier M, Villalba M, Martineau P, Laurent-Matha V, Roger P, Guiu S, Chardès T, Gros L, Liaudet-Coopman E A novel Fc-engineered cathepsin D-targeting antibody enhances ADCC, triggers tumor-infiltrating NK cell recruitment, and improves treatment with paclitaxel and enzalutamide in triple-negative breast cancer. J Immunother Cancer. 2024;12(1):e007135. doi:10.1136/jitc-2023-007135

Gouyon J, Clavié M, Raquel G-C, Ngo G, Dumy P, Etienne P, Martineau P, Pugnière M, Ahmad M, Subra G, Perrin C, Ladner Y A bioinspired approach for the modulation of electroosmotic flow and protein-surface interactions in capillary electrophoresis using silylated amino-amides blocks and covalent grafting. Electrophoresis. 2024;45(5-6):557-572. doi:10.1002/elps.202300168

Cusumano C, Deshayes E, Guiu B, De Meeus G, Carrère S, Bouillin A, Ilonca D, Éberlé M, Guillemard S, Fersing C, Sgarbura O, Quénet F Prevention of post-hepatectomy liver failure after major resection of colorectal liver metastases: is hepato-biliary scintigraphy the optimal tool?. Ann Transl Med. 2023;11(5):202. doi:10.21037/atm-22-3665

Cashin P, Esquivel J, Larsen S, Liauw W, Alzahrani N, Morris D, Kepenekian V, Sourrouille I, Tuech J-J, Ceribelli C, Doussot B, Sgarbura O, Glehen O, Fisher O Perioperative chemotherapy in colorectal cancer with peritoneal metastases: A global propensity score matched study. EClinicalMedicine. 2023;55. doi:10.1016/j.eclinm.2022.101746

Noverraz F, Robin B, Passemard S, Fauvel B, Presumey J, Rigal E, Cookson A, Chopineau J, Martineau P, Villalba M, Jorgensen C, Aubert-Pouëssel A, Morille M, Gerber-Lemaire S Novel trehalose-based excipients for stabilizing nebulized anti-SARS-CoV-2 antibody. Int J Pharm. 2023;630. doi:10.1016/j.ijpharm.2022.122463

Cassese G, Troisi R, Khayat S, Benoudifa B, Guiu B, Panaro F Liver Venous Deprivation Versus Portal Vein Embolization Before Major Hepatectomy for Colorectal Liver Metastases: A Retrospective Comparison of Short- and Medium-Term Outcomes. J Gastrointest Surg. 2023;27(2):296-305. doi:10.1007/s11605-022-05551-2

Mangeat T, Gracia M, Pichard A, Poty S, Martineau P, Robert B, Deshayes E Fc-engineered monoclonal antibodies to reduce off-target liver uptake. EJNMMI Res. 2023;13(1):81. doi:10.1186/s13550-023-01030-0

David T, Mallavialle A, Faget J, Alcaraz L, Lapierre M, du Roure P, Laurent-Matha V, Mansouri H, Jarlier M, Martineau P, Roger P, Guiu S, Chardès T, Liaudet-Coopman E Anti-cathepsin D immunotherapy triggers both innate and adaptive anti-tumour immunity in breast cancer. Br J Pharmacol. 2023-11-29. doi:10.1111/bph.16291

Tassou A, Thouaye M, Gilabert D, Jouvenel A, Leyris J-P, Sonrier C, Diouloufet L, Mechaly I, Mallié S, Bertin J, Chentouf M, Neiveyans M, Pugnière M, Martineau P, Robert B, Capdevila X, Valmier J, Rivat C Activation of neuronal FLT3 promotes exaggerated sensorial and emotional pain-related behaviors facilitating the transition from acute to chronic pain. Prog Neurobiol. 2023;222. doi:10.1016/j.pneurobio.2023.102405

Antunes A, Alvarez-Vallina L, Bertoglio F, Bouquin N, Cornen S, Duffieux F, Ferré P, Gillet R, Jorgensen C, Leick M, Maillère B, Negre H, Pelegrin M, Poirier N, Reusch D, Robert B, Serre G, Vicari A, Villalba M, Volpers C, Vuddamalay G, Watier H, Wurch T, Zabeau L, Zielonka S, Zhang B, Beck A, Martineau P 10th antibody industrial symposium: new developments in antibody and adoptive cell therapies. MAbs. 2023;15(1):2211692. doi:10.1080/19420862.2023.2211692

Genest M, Comunale F, Planchon D, Govindin P, Noly D, Vacher S, Bièche I, Robert B, Malhotra H, Schoenit A, Tashireva L, Casas J, Gauthier-Rouvière C, Bodin S Upregulated flotillins and sphingosine kinase 2 derail AXL vesicular traffic to promote epithelial-mesenchymal transition. J Cell Sci. 2022;135(7):jcs259178. doi:10.1242/jcs.259178

Giguelay A, Turtoi E, Khelaf L, Tosato G, Dadi I, Chastel T, Poul M-A, Pratlong M, Nicolescu S, Severac D, Adenis A, Sgarbura O, Carrère S, Rouanet P, Ychou M, Pourquier D, Colombo P-E, Turtoi A, Colinge J The landscape of cancer-associated fibroblasts in colorectal cancer liver metastases. Theranostics. 2022;12(17):7624-7639. doi:10.7150/thno.72853



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