Research
Epitranscriptomics & Cancer Adaptation : A.David

Activities

Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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Title  Creator  Group name  Publishing year 
A novel Fc-engineered cathepsin D-targeting antibody enhances ADCC, triggers tumor-infiltrating NK cell recruitment, and improves treatment with paclitaxel and enzalutamide in triple-negative breast cancer Desroys du Roure et al. EquipeELC 2024-01-30
The mechanosensitive TRPV2 calcium channel promotes human melanoma invasiveness and metastatic potential Shoji et al. EquipeELC 2023-02-06
Pertuzumab Plus Trastuzumab With or Without Chemotherapy Followed by Emtansine in ERBB2-Positive Metastatic Breast Cancer: A Secondary Analysis of a Randomized Clinical Trial Huober et al. EquipeELC 2023-08-10
Long-Term Results with Everolimus in Advanced Hormone Receptor Positive Breast Cancer in a Multicenter National Real-World Observational Study François-Martin et al. EquipeELC 2023-02-13
First evidence of AXL expression on circulating tumor cells in metastatic breast cancer patients: A proof-of-concept study Bardol et al. EquipeELC 2023-12-22
Design and selection of optimal ErbB-targeting bispecific antibodies in pancreatic cancer Rabia et al. EquipeELC 2023
Anti-cathepsin D immunotherapy triggers both innate and adaptive anti-tumour immunity in breast cancer David et al. EquipeELC 2023-11-29
Unusual Focal Lung Uptake without CT Abnormality on a Bone Scan: What Might It Mean? Eberlé et al. EquipeELC 2022-04-08
SPARC in cancer-associated fibroblasts is an independent poor prognostic factor in non-metastatic triple-negative breast cancer and exhibits pro-tumor activity Alcaraz et al. EquipeELC 2022-11-08
Secretion of IL1 by Dedifferentiated Melanoma Cells Inhibits JAK1-STAT3-Driven Actomyosin Contractility of Lymph Node Fibroblastic Reticular Cells Rovera et al. EquipeELC 2022-05-03
Real-world evidence of the management and prognosis of young women (?40?years) with de novo metastatic breast cancer Mallet et al. EquipeELC 2022
Pharmacokinetic Variability Drives Palbociclib-Induced Neutropenia in Metastatic Breast Cancer Patients: Drug-Drug Interactions Are the Usual Suspects Leenhardt et al. EquipeELC 2022-04-11
Impact of lobular versus ductal histology on overall survival in metastatic breast cancer: a French retrospective multicentre cohort study Dalenc et al. EquipeELC 2022-03
Hypnosis on patients treated with adjuvant chemotherapy for breast cancer: A feasibility study Fabbro et al. EquipeELC 2022-10-27
Emotional processes in partners' quality of life at various stages of breast cancer pathway: a longitudinal study Baudry et al. EquipeELC 2022-11-24
Efficacy of taxanes rechallenge in first-line treatment of early metastatic relapse of patients with HER2-negative breast cancer previously treated with a (neo)adjuvant taxanes regimen: A multicentre retrospective observational study Vasseur et al. EquipeELC 2022-10
Diagnostic Accuracy of Digital Staining ex vivo Confocal Microscopy for Diagnosing and Subtyping Basal Cell Carcinoma in Fresh Pretherapeutic Punch Biopsies: A Monocentric Prospective Study Bergeret et al. EquipeELC 2022-05-05
Correlation of the TIGIT-PVR immune checkpoint axis with clinicopathological features in triple-negative breast cancer Boissière-Michot et al. EquipeELC 2022
Association of Endocrine Therapy for HR+/ERBB2+ Metastatic Breast Cancer With Survival Outcomes Carausu et al. EquipeELC 2022-12-01
Adjustment of young women with breast cancer after chemotherapy: A mediation model of emotional competence via emotional distress Baudry et al. EquipeELC 2022-01-05
[2021 update of the GEFPICS' recommendations for HER2 status assessment in invasive breast cancer in France] Franchet et al. EquipeELC 2021-08-12
Upfront surgery or definitive radiotherapy for patients with p16-negative oropharyngeal squamous cell carcinoma. A GETTEC multicentric study Culié et al. EquipeELC 2021-02
TNFR1-d2 carrying the p.(Thr79Met) pathogenic variant is a potential novel actor of TNF?/TNFR1 signalling regulation in the pathophysiology of TRAPS Rittore et al. EquipeELC 2021-02-18
Targeting Discoidin Domain Receptors DDR1 and DDR2 overcomes matrix-mediated tumor cell adaptation and tolerance to BRAF-targeted therapy in melanoma Berestjuk et al. EquipeELC 2021-12-27
Synchronous primary neoplasia in patients with oropharyngeal cancer: Impact of tumor HPV status. A GETTEC multicentric study Milliet et al. EquipeELC 2021-01


© Institut de Recherche en Cancérologie de Montpellier - 2011 - Tous droits réservés - Mentions légales - Connexion - Conception : ID Alizés