Research
Epitranscriptomics & Cancer Adaptation : A.David

Activities

Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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Title  Creator  Group name  Publishing year 
Cellular origin and clonal evolution of human dedifferentiated liposarcoma Gruel et al. EquipeLL 2024-09-12
Bile Acid Metabolism Mediates Cholesterol Homeostasis and Promotes Tumorigenesis in Clear Cell Renal Cell Carcinoma Riscal et al. EquipeLL 2024-05-15
A metabolic crosstalk between liposarcoma and muscle sustains tumor growth Manteaux et al. EquipeLL 2024-09-12
Dengue virus M and E proteins belonging to genotype II (Cosmopolitan) of serotype 2 are influenced by the nature of M residue 36 Decotter et al. EquipeLL 2023-07
Combining the antianginal drug perhexiline with chemotherapy induces complete pancreatic cancer regression in vivo Reyes-Castellanos et al. EquipeLL 2023-06-16
RIP140 inhibits glycolysis-dependent proliferation of breast cancer cells by regulating GLUT3 expression through transcriptional crosstalk between hypoxia induced factor and p53 Jacquier et al. EquipeLL 2022-05-03
High Glucose Induces in HK2 Kidney Cells an IFN-Dependent ZIKV Antiviral Status Fueled by Viperin Reslan et al. EquipeLL 2022-07-01
Glucagon signaling via supraphysiologic GCGR can reduce cell viability without stimulating gluconeogenic gene expression in liver cancer cells Godfrey et al. EquipeLL 2022-02-05
GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment Missiaen et al. EquipeLL 2022-08-02
Author Correction: The SARS-CoV-2 spike residues 616/644 and 1138/1169 delineate two antibody epitopes in COVID-19 mRNA COMIRNATY vaccine (Pfizer/BioNTech) Andries et al. EquipeLL 2022-04-20
Zika Virus Growth in Human Kidney Cells Is Restricted by an Elevated Glucose Level Reslan et al. EquipeLL 2021-03-02
Zika E Glycan Loop Region and Guillain-Barré Syndrome-Related Proteins: A Possible Molecular Mimicry to Be Taken in Account for Vaccine Development Lebeau et al. EquipeLL 2021-03-19
The p53 Pathway and Metabolism: The Tree That Hides the Forest Lahalle et al. EquipeLL 2021-01-04
The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes Lacroix et al. EquipeLL 2021-12-02
Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia Stuani et al. EquipeLL 2021-05-03
Glycogen metabolism is dispensable for tumour progression in clear cell renal cell carcinoma Xie et al. EquipeLL 2021-03
Cholesterol Auxotrophy as a Targetable Vulnerability in Clear Cell Renal Cell Carcinoma Riscal et al. EquipeLL 2021-12-01
?133p53? isoform pro-invasive activity is regulated through an aggregation-dependent mechanism in cancer cells Arsic et al. EquipeLL 2021-09-15
Zika Virus Inhibits IFN-? Response by Human Plasmacytoid Dendritic Cells and Induces NS1-Dependent Triggering of CD303 (BDCA-2) Signaling Bos et al. EquipeLL 2020
Zika M Oligopeptide ZAMP Confers Cell Death-Promoting Capability to a Soluble Tumor-Associated Antigen through Caspase-3/7 Activation Vanwalscappel et al. EquipeLL 2020-12-16
Targeting MDM2-dependent serine metabolism as a therapeutic strategy for liposarcoma Cissé et al. EquipeLL 2020-06-10
TAG-RNAi overcomes off-target effects in cancer models Champagne et al. EquipeLL 01 2020
Simultaneous Measurement of Metabolite Concentration and Isotope Incorporation by Mass Spectrometry Heuillet et al. EquipeLL 04 21, 2020
Metabolic functions of the tumor suppressor p53: Implications in normal physiology, metabolic disorders, and cancer Lacroix et al. EquipeLL 03 2020
FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome Li et al. EquipeLL 2020-06


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