Research
Epitranscriptomics & Cancer Adaptation : A.David

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Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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29 Items
Title  Creator  Group name  Publishing year 
E4F1 coordinates pyruvate metabolism and the activity of the elongator complex to ensure translation fidelity during brain development Di Michele et al. EquipeLLC 2025-01-02
ATR inhibition potentiates FOLFIRINOX cytotoxic effect in models of pancreatic ductal adenocarcinoma by remodelling the tumour microenvironment Bruciamacchie et al. EquipeCG 2024-11-29
RIP140 inhibits glycolysis-dependent proliferation of breast cancer cells by regulating GLUT3 expression through transcriptional crosstalk between hypoxia induced factor and p53 Jacquier et al. EquipeVC 2022-05-03
TNFR1-d2 carrying the p.(Thr79Met) pathogenic variant is a potential novel actor of TNF?/TNFR1 signalling regulation in the pathophysiology of TRAPS Rittore et al. Informatique 2021-02-18
Metastatic colorectal cancer cells maintain the TGF? program and use TGFBI to fuel angiogenesis Chiavarina et al. EquipeAT 2021
Quantification of HER1, HER2 and HER3 by time-resolved Förster resonance energy transfer in FFPE triple-negative breast cancer samples Ho-Pun-Cheung et al. EquipeELC 2020-02
PSMB10, the last immunoproteasome gene missing for PRAAS Sarrabay et al. Informatique Mar 2020
POLR1B and neural crest cell anomalies in Treacher Collins syndrome type 4 Sanchez et al. Informatique Mar 2020
Notch inhibition overcomes resistance to tyrosine kinase inhibitors in EGFR-driven lung adenocarcinoma Bousquet Mur et al. EquipeAM 2020-02-03
Neutrophil Extracellular Traps and By-Products Play a Key Role in COVID-19: Pathogenesis, Risk Factors, and Therapy Thierry and Roch EquipeMY Sep 11, 2020
Postdoctoral Position in Modeling of the Tumor Microenvironment   Offres-emploi 29/11/2019
Intestinal Epithelium & Environment Interactions : Roles in Inflammation & Tumorigenesis Audrey FERRAND Seminaires_Externes Jeudi 10 Octobre 2019
Critical role for TRIM28 and HP1?/? in the epigenetic control of T cell metabolic reprograming and effector differentiation Gehrmann et al. EQUIPEFC Dec 17, 2019
Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies Perrot et al. EquipeNB May 21, 2019
The mouse HP1 proteins are not required for cell viability but are essential for preventing liver tumorigenesis Saksouk et al. EQUIPEFC janvier 1, 2018
In mammalian foetal testes, SOX9 regulates expression of its target genes by binding to genomic regions with conserved signatures Rahmoun et al. EQUIPEFC Jul 07, 2017
[CCAFU french national guidelines 2016-2018 on prostate cancer] Rozet et al. EquipeAP Nov 2016
TRIM28 represses transcription of endogenous retroviruses in neural progenitor cells Fasching et al. EQUIPEFC Jan 06, 2015
The Wnt-target gene Dlk-1 is regulated by the Prmt5-associated factor Copr5 during adipogenic conversion. - PubMed - NCBI   EQUIPEFC Feb 13, 2015
Shigella flexneri targets the HP1? subcode through the phosphothreonine lyase OspF. - PubMed - NCBI   EQUIPEFC Sep 12,2014
The backbone model of the Arabis mosaic virus reveals new insights into functional domains of Nepovirus capsid Lai-Kee-Him et al. Informatique Jan 30 2013
FATP1 inhibits 11-cis retinol formation via interaction with the visual cycle retinoid isomerase RPE65 and lecithin:retinol acyltransferase Guignard et al. Informatique Jun 11 2010
Functional role of the conserved proline in helix 6 of the human bradykinin B2 receptor Haffemayer et al. Informatique Feb 22, 2008
Crosslinking photosensitized by a ruthenium chelate as a tool for labeling and topographical studies of G-protein-coupled receptors Duroux-Richard et al. Informatique Jan 2005
Identification by MALDI-TOF mass spectrometry of 17 alpha-bromoacetamidopropylestradiol covalent attachment sites on estrogen receptor alpha Mattras et al. Informatique Dec 31, 2002
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29 Items


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Located in the Parc Euromédecine, the Institut de Recherche en Cancérologie de Montpellier (U1194) is located on the Val d'Aurelle Campus (ICM, Institut régional du Cancer Montpellier/ Val d'Aurelle).

U1194 Research Centre supported by Inserm, the University of Montpellier and the Institut du Cancer de Montpellier (ICM)

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