Research
Epitranscriptomics & Cancer Adaptation : A.David

Activities

Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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26 Items
Title  Creator  Group name  Publishing year 
Multi-Level Control of the ATM/ATR-CHK1 Axis by the Transcription Factor E4F1 in Triple-Negative Breast Cancer Batnini et al. EquipeLLC 2022-08-16
Computational Model of Heterogeneity in Melanoma: Designing Therapies and Predicting Outcomes Hodgkinson et al. EquipeLLC 2022
The p53 Pathway and Metabolism: The Tree That Hides the Forest Lahalle et al. EquipeLLC 2021-01-04
The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes Lacroix et al. EquipeLLC 2021-12-02
High Resolution Episcopic Microscopy for Qualitative and Quantitative Data in Phenotyping Altered Embryos and Adult Mice Using the New "Histo3D" System Wendling et al. EquipeLLC 2021-07-01
DEXOM: Diversity-based enumeration of optimal context-specific metabolic networks Rodríguez-Mier et al. EquipeLLC 2021-2-11
The MEK5-ERK5 Kinase Axis Controls Lipid Metabolism in Small-Cell Lung Cancer Cristea et al. EquipeLLC 2020-03-15
Targeting MDM2-dependent serine metabolism as a therapeutic strategy for liposarcoma Cissé et al. EquipeLLC 2020-06-10
Metabolic functions of the tumor suppressor p53: Implications in normal physiology, metabolic disorders, and cancer Lacroix et al. EquipeLLC 2020-03
Spatio-Genetic and phenotypic modelling elucidates resistance and re-sensitisation to treatment in heterogeneous melanoma Hodgkinson et al. EquipeLLC 04/2019
Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53 Arena et al. EquipeLLC Feb 15, 2018
MDM2 controls gene expression independently of p53 in both normal and cancer cells Arena et al. EquipeLLC Sep 2018
?-catenin oncogenic activation rewires fatty acid catabolism to fuel hepatocellular carcinoma Montagner et al. EquipeLLC Aug 04, 2018
Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia Boutzen et al. EquipeLLC Apr 4 2016
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Klionsky et al. EquipeLLC Jan 2 2016
E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis Goguet-Rubio et al. EquipeLLC Sep 27 2016
Chromatin-bound MDM2, a new player in metabolism Riscal et al. EquipeLLC 2016
The transcription factor E4F1 coordinates CHK1-dependent checkpoint and mitochondrial functions Rodier et al. EquipeLLC Apr 14 2015
Numb is required to prevent p53-dependent senescence following skeletal muscle injury Le Roux et al. EquipeLLC 2015
Description of an optimized ChIP-seq analysis pipeline dedicated to genome wide identification of E4F1 binding sites in primary and transformed MEFs Houles et al. EquipeLLC Sep 2015
AMPK/HuR-Driven IL-20 Post-Transcriptional Regulation in Psoriatic Skin Garcin et al. EquipeLLC Jun 15 2015
E4F1 deficiency results in oxidative stress-mediated cell death of leukemic cells Hatchi et al. EquipeLLC Jul 4 2011
E4F1 connects the Bmi1-ARF-p53 pathway to epidermal stem cell-dependent skin homeostasis Caramel et al. EquipeLLC Mar 15 2011
[Elastase 2, a key player in the integrity of the epidermal barrier and in Netherton syndrome] Bonnart et al. EquipeLLC Aug-Sep 2010
Par2 inactivation inhibits early production of TSLP, but not cutaneous inflammation, in Netherton syndrome adult mouse model Briot et al. EquipeLLC Dec 2010
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26 Items


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Located in the Parc Euromédecine, the Institut de Recherche en Cancérologie de Montpellier (U1194) is located on the Val d'Aurelle Campus (ICM, Institut régional du Cancer Montpellier/ Val d'Aurelle).

U1194 Research Centre supported by Inserm, the University of Montpellier and the Institut du Cancer de Montpellier (ICM)

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