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Epitranscriptomics & Cancer Adaptation : A.David

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Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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Group name EquipeJPP
Item Type Journal Article
Title (Pre)treatment risk factors for late fatigue and fatigue trajectories following radiotherapy for breast cancer
Creator Rosas et al.
Author Juan C. Rosas
Author Miguel E. Aguado-Barrera
Author David Azria
Author Erik Briers
Author Rebecca Elliott
Author Marie-Pierre Farcy-Jacquet
Author Alexandra Giraldo
Author Sara Gutiérrez-Enríquez
Author Tiziana Rancati
Author Tim Rattay
Author Victoria Reyes
Author Barry Rosenstein
Author Dirk De Ruysscher
Author Elena Sperk
Author Hilary Stobart
Author Christopher Talbot
Author Ana Vega
Author Begoña Taboada-Valladares
Author Liv Veldeman
Author Tim Ward
Author Adam Webb
Author Catharine West
Author Jenny Chang-Claude
Author Petra Seibold
Abstract Fatigue is common in breast-cancer survivors. Our study assessed fatigue longitudinally in breast cancer patients receiving adjuvant radiotherapy (RT) and aimed to identify risk factors associated with long-term fatigue and underlying fatigue trajectories. Fatigue was measured in a prospective multicenter cohort (REQUITE) using the Multidimensional Fatigue Inventory (MFI-20) and analyzed using mixed models. Multivariable logistic models identified factors associated with fatigue dimensions at 2?years post-RT and latent class growth analysis identified individual fatigue trajectories. A total of 1443, 1302, 1203 and 1098 patients completed the MFI-20 at baseline, end of RT, after 1 and 2?years. Overall, levels of fatigue significantly increased from baseline to end of RT for all fatigue dimensions (P?
Publication International Journal of Cancer
Volume 153
Issue 9
Pages 1579-1591
Date 2023-11-01
Journal Abbr Int J Cancer
Language eng
DOI 10.1002/ijc.34640
ISSN 1097-0215
Library Catalog PubMed
Extra Number: 9 PMID: 37403702
Tags breast cancer, Breast Neoplasms, clinic, determinants, Fatigue, Female, Humans, longitudinal trajectories, Pain, Prospective Studies, Quality of Life, Risk Factors, Sleep Initiation and Maintenance Disorders
Date Added 2023/11/23 - 12:48:37
Date Modified 2023/11/23 - 12:48:37
Notes and Attachments PubMed entry (Attachment)


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