| Added by | standudu |
|---|---|
| Group name | EquipeCTCS |
| Item Type | Journal Article |
| Title | [Breast cancer screening: On our way to the future] |
| Creator | Delaloge et al. |
| Author | Suzette Delaloge |
| Author | Thomas Bachelot |
| Author | François-Clément Bidard |
| Author | Marc Espie |
| Author | Etienne Brain |
| Author | Hervé Bonnefoi |
| Author | Joseph Gligorov |
| Author | Florence Dalenc |
| Author | Anne-Claire Hardy-Bessard |
| Author | David Azria |
| Author | Jean-Philippe Jacquin |
| Author | Jérôme Lemonnier |
| Author | William Jacot |
| Author | Anthony Goncalves |
| Author | Charles Coutant |
| Author | Gérard Ganem |
| Author | Thierry Petit |
| Author | Frédérique Penault-Llorca |
| Author | Marc Debled |
| Author | Mario Campone |
| Author | Christelle Levy |
| Author | Bruno Coudert |
| Author | Alain Lortholary |
| Author | Laurence Venat-Bouvet |
| Author | Julien Grenier |
| Author | Hugues Bourgeois |
| Author | Bernard Asselain |
| Author | Johanna Arvis |
| Author | Martine Castro |
| Author | Anne Tardivon |
| Author | David G. Cox |
| Author | Patrick Arveux |
| Author | Corinne Balleyguier |
| Author | Fabrice André |
| Author | Roman Rouzier |
| Abstract | Breast cancer remains a potentially lethal disease, which requires aggressive treatments and is associated with long-term consequences. Its prognosis is linked to both tumor biology and burden at diagnosis. Although treatments have allowed important improvements in prognosis over the past 20 years, breast cancer screening remains necessary. Mammographic screening allows earlier stage diagnoses and a decrease of breast cancer specific mortality. However, breast cancer screening modalities should be revised with the objective to address demonstrated limitations of mammographic screening (limited benefit, imperfect sensitivity and specificity, overdiagnoses, radiation-induced morbidity). Furthermore, both objective and perceived performances of screening procedures should be improved. Numerous large international efforts are ongoing, leading to scientific progresses that should have rapid clinical implications in this area. Among them is improvement of imaging techniques performance, development of real time diagnosis, and development of new non radiological screening techniques such as the search for circulating tumor DNA, development of biomarkers able to allow precise risk evaluation and stratified screening. As well, overtreatment is currently addressed by biomarker-based de-escalation clinical trials. These advances need to be associated with strong societal support, as well as major paradigm changes regarding the way health and cancer prevention is perceived by individuals. |
| Publication | Bulletin Du Cancer |
| Volume | 103 |
| Issue | 9 |
| Pages | 753-763 |
| Date | 09 2016 |
| Journal Abbr | Bull Cancer |
| Language | fre |
| DOI | 10.1016/j.bulcan.2016.06.005 |
| ISSN | 1769-6917 |
| Short Title | [Breast cancer screening |
| Library Catalog | PubMed |
| Extra | PMID: 27473920 |
| Tags | Biomarkers, Biomarkers, Tumor, Biomarqueurs, Breast Neoplasms, Cancer du sein, Dépistage, Early Detection of Cancer, Female, France, Humans, Mammography, Personalized, Personnalisé, review, Risk, Risk Assessment, Risque, Sensitivity and Specificity, Tumor Burden |
| Date Added | 2019/05/31 - 15:59:51 |
| Date Modified | 2019/05/31 - 16:00:28 |
| Notes and Attachments | PubMed entry (Attachment) |
Institut de Recherche en Cancérologie de
