| Added by | JPPOUGET |
|---|---|
| Group name | EquipeJPP |
| Item Type | Journal Article |
| Title | Extracellular vesicles role in radio(nuclide)therapy |
| Creator | Constanzo and Pouget |
| Author | J. Constanzo |
| Author | J.-P. Pouget |
| Abstract | Conventional radiation therapy can restore the ability of cells to undergo immunogenic cell death. Recent preclinical studies suggest that targeted radionuclide therapy, which delivers radiation to tumors at a continuous low dose rate, also stimulates the immune system and offers a promising approach for overcoming resistance to immune checkpoint inhibitors. In this context, we examined the growing body of preclinical and clinical findings showing that the immune system can be activated by the release of extracellular vesicles from irradiated cells, contributing to the antitumor immunity. |
| Publication | Journal of Radiation Research |
| Volume | 65 |
| Issue | Supplement_1 |
| Pages | i6-i14 |
| Date | 2024-12-16 |
| Journal Abbr | J Radiat Res |
| Language | eng |
| DOI | 10.1093/jrr/rrae084 |
| ISSN | 1349-9157 |
| Library Catalog | PubMed |
| Extra | PMID: 39679885 PMCID: PMC11647936 |
| Tags | Animals, bystander, Extracellular Vesicles, Humans, Neoplasms, radioimmunotherapy, Radioisotopes |
| Date Added | 2024/12/20 - 02:11:58 |
| Date Modified | 2024/12/20 - 02:11:58 |
| Notes and Attachments | PubMed entry (Attachment) |
Institut de Recherche en Cancérologie de
