| Added by | tchardes |
|---|---|
| Group name | EquipeELC |
| Item Type | Journal Article |
| Title | Real-world evidence of the management and prognosis of young women (?40?years) with de novo metastatic breast cancer |
| Creator | Mallet et al. |
| Author | Amélie Mallet |
| Author | Christelle Levy |
| Author | Barbara Pistilli |
| Author | Etienne Brain |
| Author | David Pasquier |
| Author | Marc Debled |
| Author | Jean Christophe Thery |
| Author | Isabelle Desmoulins |
| Author | Thibault De La Motte Rouge |
| Author | Christelle Faure |
| Author | Jean Marc Ferrero |
| Author | Jean Christophe Eymard |
| Author | Marie Ange Mouret-Reynier |
| Author | Anne Patsouris |
| Author | Paul Cottu |
| Author | Florence Dalenc |
| Author | Thierry Petit |
| Author | Olivier Payen |
| Author | Lionel Uwer |
| Author | Séverine Guiu |
| Author | Jean Sébastien Frenel |
| Abstract | Background: Breast cancer (BC) in young women merits a specific approach given the associated fertility, genetic and psychosocial issues. De novo metastatic breast cancer (MBC) in young women is an even more serious condition, with limited data available. Methods: We evaluated management of women aged ?40?years with de novo MBC in a real-life national multicentre cohort of 22,463 patients treated between 2008 and 2016 (NCT0327531). Our primary objective was to compare overall survival (OS) in young women versus women aged 41-69?years. The secondary objectives were to compare first-line progression-free survival (PFS1) and to describe treatment patterns. Results: Of the 4524 women included, 598 (13%) were ?40?years. Median age at MBC diagnosis was 36?years (range?=?20-40). Compared with women aged 41-69?years, young women had more grade III tumours (49% versus 35.7%, p? |
| Publication | Therapeutic Advances in Medical Oncology |
| Volume | 14 |
| Pages | 17588359211070362 |
| Date | 2022 |
| Journal Abbr | Ther Adv Med Oncol |
| Language | eng |
| DOI | 10.1177/17588359211070362 |
| ISSN | 1758-8340 |
| Library Catalog | PubMed |
| Extra | PMID: 35082924 PMCID: PMC8785354 |
| Tags | clinic, de novo, metastatic breast cancer, real-life, young women |
| Date Added | 2022/02/07 - 15:22:50 |
| Date Modified | 2022/02/08 - 09:22:55 |
| Notes and Attachments | PubMed entry (Attachment) Version acceptée (Attachment) |
Institut de Recherche en Cancérologie de
