| Added by | pmartino |
|---|---|
| Group name | EquipePM |
| Item Type | Journal Article |
| Title | Prognosis of poorly cohesive gastric cancer after complete cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy (CYTO-CHIP study) |
| Creator | Bonnot et al. |
| Author | P. E. Bonnot |
| Author | A. Lintis |
| Author | F. Mercier |
| Author | N. Benzerdjeb |
| Author | G. Passot |
| Author | M. Pocard |
| Author | B. Meunier |
| Author | J. M. Bereder |
| Author | K. Abboud |
| Author | F. Marchal |
| Author | F. Quenet |
| Author | S. Msika |
| Author | C. Arvieux |
| Author | N. Pirro |
| Author | R. Wernert |
| Author | P. Rat |
| Author | J. Gagnière |
| Author | J. H. Lefevre |
| Author | T. Courvoisier |
| Author | R. Kianmanesh |
| Author | D. Vaudoyer |
| Author | M. Rivoire |
| Author | L. Villeneuve |
| Author | G. Piessen |
| Author | O. Glehen |
| Abstract | BACKGROUND: The incidence of gastric poorly cohesive carcinoma (PCC) is increasing. The prognosis for patients with peritoneal metastases remains poor and the role of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is controversial. The aim was to clarify the impact of gastric PCC with peritoneal metastases treated by CRS with or without HIPEC. METHODS: All patients with peritoneal metastases from gastric cancer treated with CRS with or without HIPEC, in 19 French centres, between 1989 and 2014, were identified from institutional databases. Clinicopathological characteristics and outcomes were compared between PCC and non-PCC subtypes, and the possible benefit of HIPEC was assessed. RESULTS: In total, 277 patients were included (188 PCC, 89 non-PCC). HIPEC was performed in 180 of 277 patients (65 per cent), including 124 of 188 with PCC (66 per cent). Median overall survival (OS) was 14.7 (95 per cent c.i. 12.7 to 17.3) months in the PCC group versus 21.2 (14.7 to 36.4) months in the non-PCC group (P? |
| Publication | The British Journal of Surgery |
| Volume | 108 |
| Issue | 10 |
| Pages | 1225-1235 |
| Date | 2021-10-23 |
| Journal Abbr | Br J Surg |
| Language | eng |
| DOI | 10.1093/bjs/znab200 |
| ISSN | 1365-2168 |
| Library Catalog | PubMed |
| Extra | 00002 PMID: 34498666 |
| Tags | Adult, Aged, Aged, 80 and over, clinic, Cytoreduction Surgical Procedures, Disease-Free Survival, Female, Humans, Kaplan-Meier Estimate, Male, Middle Aged, Ovarian Neoplasms, Peritoneal Neoplasms, Prognosis, Retrospective Studies, Stomach Neoplasms, Young Adult |
| Date Added | 2022/02/04 - 18:06:56 |
| Date Modified | 2022/02/04 - 18:09:48 |
| Notes and Attachments | PubMed entry (Attachment) |
Institut de Recherche en Cancérologie de
