| Added by | JPPOUGET |
|---|---|
| Group name | EquipeJPP |
| Item Type | Journal Article |
| Title | Specificities of clinical research in radiotherapy |
| Creator | Hennequin et al. |
| Author | C. Hennequin |
| Author | D. Azria |
| Author | P. Blanchard |
| Author | G. Créhange |
| Author | É Deutsch |
| Author | A. Lisbona |
| Author | É Moyal |
| Author | D. Pasquier |
| Author | L. Roca |
| Author | S. Supiot |
| Author | P. Giraud |
| Abstract | The aim of this review is to present the specificities of clinical research in radiation oncology. Objectives are similar to all research in oncology: to improve the efficacy and to decrease toxic effects. Phase III trials remain the main methodology to demonstrate an improvement in efficiency, but phase I-II and registers are also important tools to validate an improvement in the therapeutic index with new technologies. In this article we discuss the special features of end-points, selection of population, and design for radiation oncology clinical trials. Quality control of delivered treatments is an important component of these protocols. Financial issues are also discussed, in the particular context of France. |
| Publication | Cancer Radiotherapie: Journal De La Societe Francaise De Radiotherapie Oncologique |
| Volume | 26 |
| Issue | 1-2 |
| Pages | 104-107 |
| Date | 2022 |
| Journal Abbr | Cancer Radiother |
| Language | eng |
| DOI | 10.1016/j.canrad.2021.11.011 |
| ISSN | 1769-6658 |
| Library Catalog | PubMed |
| Extra | Number: 1-2 PMID: 34953712 |
| Tags | Biomedical Research, clinic, Clinical research, Clinical Trials as Topic, France, French society for radiation oncology, Guidelines, Health Physics, Humans, Patient Selection, Progression-Free Survival, Quality of Life, Radiation Oncology, Radiothérapie, Radiotherapy, Radiotherapy Dosage, Recherche, Recommandations, Research Design, Research Support as Topic, Société française de radiothérapie oncologique |
| Date Added | 2023/11/23 - 12:48:17 |
| Date Modified | 2023/11/23 - 12:48:17 |
| Notes and Attachments | PubMed entry (Attachment) |
Institut de Recherche en Cancérologie de
