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Epitranscriptomics & Cancer Adaptation : A.David

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Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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Added by informatique.ircm
Group name Offres-emploi
Item Type Thesis
Title Postdoctoral Position in Modeling of the Tumor Microenvironment
Abstract The Colinge Laboratory Cancer Bioinformatics and Systems Biology at IRCM (Cancer Research Institute of Montpellier) is looking for a talented postdoctoral fellow to work on the evolution of the tumor microenvironment (TME) in response to therapy. This computational work will build upon on-going developments conducted in the lab to infer cellular interactions taking place in the TME. Both single-cell and bulk transcriptomics configurations will be considered. A significant part of the research will relate to lung adenocarcinoma and involve a consortium of expert laboratories in lung cancer and mouse models thereof, animal computer tomography, and 3D imaging. The postdoc position is funded for three years; a 1-year contract will be offered first and extended for another two years based on performance. Preferred qualifications are a bioinformatics Ph.D. with solid computational skills or a mathematics, physics, or computer science Ph.D. with strong interests in life science applications. Interested applicants should e-mail their CV, a letter of motivation, and the names and e-mails of 2 references to Prof Jacques Colinge (jacques.colinge@inserm.fr). Applications will be studied immediately. Selected publications ? Alame et al., The molecular landscape and microenvironment of salivary duct carcinoma reveal new therapeutic opportunities, bioRxiv, 2019 ? Lehmann et al., In Vivo Large-Scale Mapping Of Protein Turnover In The Human Cerebrospinal Fluid, bioRxiv, 2019 ? Blomen et al. Gene essentiality and synthetic lethality in haploid human cells. Science, 2015 ? Pichlmair et al. Viral immune modulators perturb the human molecular network by common and unique strategies, Nature, 2012 ? Stukalov et al. Deconvolution of targeted protein-protein interaction maps. J Proteome Res, 2012
Date 29/11/2019
Extra jacques.colinge@inserm.fr
Date Added 2019/11/29 - 14:23:21
Date Modified 2019/11/29 - 14:26:59


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