| Added by | llecam |
|---|---|
| Group name | EquipeLLC |
| Item Type | Journal Article |
| Title | Chromatin-bound MDM2, a new player in metabolism |
| Creator | Riscal et al. |
| Author | Romain Riscal |
| Author | Laurent Le Cam |
| Author | Laetitia K. Linares |
| Abstract | The oncoprotein MDM2 is recognized as a major negative regulator of the p53 tumor suppressor but growing evidence indicates that its oncogenic activities extend beyond p53. We show that MDM2 is recruited to chromatin independently of p53 to regulate a transcriptional program implicated in amino acid metabolism and redox homeostasis. |
| Publication | Molecular & Cellular Oncology |
| Volume | 3 |
| Issue | 5 |
| Pages | e1210560 |
| Date | 2016 |
| Journal Abbr | Mol Cell Oncol |
| Language | eng |
| DOI | 10.1080/23723556.2016.1210560 |
| ISSN | 2372-3556 |
| Library Catalog | PubMed |
| Extra | PMID: 27857973 PMCID: PMC5068176 |
| Tags | redox, review |
| Date Added | 2022/08/30 - 22:50:33 |
| Date Modified | 2022/08/30 - 22:50:48 |
| Notes and Attachments | PubMed entry (Attachment) Texte intégral (Attachment) |
Institut de Recherche en Cancérologie de
