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Epitranscriptomics & Cancer Adaptation : A.David

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Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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Added by standudu
Last modified by mollevi
Group name EquipeCTCS
Item Type Journal Article
Title [Breast surgeon role in the management of high-risk breast lesions]
Creator Colombo et al.
Author P. E. Colombo
Author A. Vincent-Salomon
Author M. C. Chateau
Author A. Mourregot
Author M. Gutowski
Author G. Laffargue
Author B. Masson
Author A. Maran-Gonzalez
Author P. Rouanet
Abstract Diagnostics of high-risk breast lesions have increased these last years with the augmentation of breast percutaneous biopsies. They are lesions that confer an enlarged risk of breast cancer, either because of an increased probability of finding cancer after open surgery, a possible evolution toward in situ or invasive cancer, or because of an increased probability of developing breast cancer over the long term. Much progress has been made these last years in their histological diagnostic, classification and pathogenesis. Nevertheless, no consensus exists to date on the management of these "high-risk" lesions. In particular, surgical indications and follow-up modalities remain controversial for each histological type. In this review, the principal factors that could impact surgical decision and long-term follow-up are discussed with areas of controversy highlighted.
Publication Bull Cancer
Volume 101
Pages 718-29
Date Jul-Aug 2014
Journal Abbr Bulletin du cancer
DOI 10.1684/bdc.2014.2010
ISSN 1769-6917 (Electronic) 0007-4551 (Linking)
Tags Age Factors, Biopsy, Breast Neoplasms/*pathology/*surgery, Breast/*pathology, Calcinosis/radiography, Carcinoma in Situ/pathology/surgery, Carcinoma, Lobular/pathology/surgery, Cicatrix/etiology/pathology, Epithelial Cells/pathology, Female, Humans, Hyperplasia/pathology/radiography, Metaplasia/pathology, Papilloma, Intraductal/pathology/surgery, Population Surveillance, Precancerous Conditions/*pathology/surgery, Radiation Injuries/etiology/pathology/surgery, Risk
Date Added 2018/11/14 - 15:24:46
Date Modified 2018/11/14 - 15:24:46
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25091655 (Attachment)


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