| Added by | André Pèlegrin |
|---|---|
| Last modified by | standudu |
| Group name | EquipeAP |
| Item Type | Journal Article |
| Title | [Indications and outlooks of radiohormonal therapy of high-risk prostate cancers] |
| Creator | Latorzeff et al. |
| Author | I. Latorzeff |
| Author | P. Sargos |
| Author | G. Créhange |
| Author | D. Azria |
| Author | A. Hasbini |
| Author | T. Dubergé |
| Author | A. Toledano |
| Author | P. Graff-Cailleaud |
| Author | O. Chapet |
| Author | C. Hennequin |
| Author | R. de Crevoisier |
| Author | S. Supiot |
| Author | D. Pasquier |
| Abstract | Prostate cancer is a sensitive adenocarcinoma, in more than 80% of cases, to chemical castration, due to its hormone dependence. Locally advanced and/or high-risk cancer is defined based on clinical stage, initial prostate specific antigen serum concentration value or high Gleason score. Hormone therapy associated with radiation therapy is the standard of management and improves local control, reduces the risk of distant metastasis and improves specific and overall survival. Duration of hormone therapy, dose level of radiation therapy alone or associated with brachytherapy are controversial data in the literature. The therapeutic choice, multidisciplinary, depends on the age and comorbidity of the patient, the prognostic criteria of the pathology and the urinary function of the patient. Current research focuses on optimizing local and distant control of these aggressive forms and incorporates neoadjuvant or adjuvant chemotherapy and also new hormone therapies. |
| Publication | Cancer Radiotherapie: Journal De La Societe Francaise De Radiotherapie Oncologique |
| Date | Feb 11, 2020 |
| Journal Abbr | Cancer Radiother |
| Language | fre |
| DOI | 10.1016/j.canrad.2019.06.018 |
| ISSN | 1769-6658 |
| Library Catalog | PubMed |
| Extra | 00000 PMID: 32057646 |
| Tags | Cancer de la prostate de haut risque, Chemotherapy, Chimiothérapie, High-risk, Hormone therapy, Hormonothérapie, Prostate, Radiothérapie, Radiotherapy |
| Date Added | 2020/02/17 - 11:32:52 |
| Date Modified | 2020/02/17 - 12:00:00 |
| Notes and Attachments | PubMed entry (Attachment) |
Institut de Recherche en Cancérologie de
