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Epitranscriptomics & Cancer Adaptation : A.David

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Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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Added by mollevi
Last modified by celine.gongora
Group name EquipeCG
Item Type Journal Article
Title [Non-surgical treatment modalities available for the treatment of upper tract urothelial carcinomas: state-of-the-art for the yearly scientific report of the French National Association of Urology]
Creator Audenet et al.
Author F. Audenet
Author M. Roupret
Author N. Houede
Author P. Colin
Abstract INTRODUCTION: Our purpose was to provide a state-of-the-art regarding the different non-surgical treatment modalities available for urologists in the modern management of upper urinary tract carcinoma (UTUC). MATERIALS AND METHODS: A systematic review of the literature was carried out on Medline and Embase databases: urinary tract; urothelial carcinoma; ureteral cancer; renal pelvis cancer; chemotherapy; radiotherapy; instillation. RESULTS: The medical treatment of UTUC is based on the extrapolation of data coming from bladder cancer studies. It is based on instillation of topical agents in the upper tract, chemotherapy or radiotherapy. However, the fact that UTUCs are scarce and the lack of randomized prospective trials do not provide definitive conclusions on the impact of these treatments. CONCLUSION: The optimal medical management of UTUC is mostly based on expert's opinion so far in combination with the surgical treatment. The international collaborations for UTUC that have been developed in recent years should provide concrete answers in the near future.
Publication Prog Urol
Volume 24
Pages 1030-40
Date Nov 2014
Journal Abbr Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie
DOI 10.1016/j.purol.2014.07.002
ISSN 1166-7087 (Print) 1166-7087 (Linking)
Tags review
Date Added 2018/07/20 - 10:05:58
Date Modified 2019/05/14 - 13:53:21
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