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Epitranscriptomics & Cancer Adaptation : A.David

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Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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Added by liaudet-coopman
Group name EquipeELC
Item Type Journal Article
Title [Pre-analytical stage for biomarker assessment in breast cancer: 2014 update of the GEFPICS' guidelines in France]
Creator MacGrogan et al.
Author Marie-Christine Mathieu
Author Bruno Poulet
Author Frédérique Penault-Llorca
Author Anne Vincent-Salomon
Author Pascal Roger
Author Isabelle Treilleux
Author Alexander Valent
Author Martine Antoine
Author Catherine Bor
Author Eva Brabencova
Author Emmanuelle Charafe-Jauffret
Author Marie-Pierre Chenard
Author Marie-Mélanie Dauplat
Author Paul Delrée
Author Mojgan Devouassoux
Author Maryse Fiche
Author Marie-Eve Fondrevelle
Author Viviana Fridman
Author Christian Garbar
Author Pascal Genin
Author Jean-Pierre Ghnassia
Author Juliette Haudebourg
Author Sophie Laberge-Le Couteulx
Author Delphine Loussouarn
Author Aurélie Maran-Gonzalez
Author Myriam Marcy
Author Patrick Michenet
Author Christine Sagan
Author Martine Trassard
Author Véronique Verriele
Author Laurent Arnould
Author Magali Lacroix-Triki
Abstract Biomarker assessment of breast cancer tumor samples is part of the routine workflow of pathology laboratories. International guidelines have recently been updated, with special regards to the pre-analytical steps that are critical for the quality of immunohistochemical and in situ hybridization procedures, whatever the biomarker analyzed. Fixation and specimen handling protocols must be standardized, validated and carefully tracked. Cooperation and training of the personnel involved in the specimen workflow (e.g. radiologists, surgeons, nurses, technicians and pathologists) are of paramount importance. The GEFPICS' update of the recommendations herein details and comments the different steps of the pre-analytical process. Application of these guidelines and participation to quality insurance programs are mandatory to ensure the correct evaluation of oncotheranostic biomarkers.
Publication Annales De Pathologie
Volume 34
Issue 5
Pages 366-372
Date Oct 2014
Journal Abbr Ann Pathol
Language fre
DOI 10.1016/j.annpat.2014.08.017
ISSN 0242-6498
Short Title [Pre-analytical stage for biomarker assessment in breast cancer
Library Catalog PubMed
Extra PMID: 25439989
Tags Biomarker, Biomarkers, Tumor, Biomarqueur, Breast Neoplasms, Cancer du sein, clinic, Female, Fixation, Fixative, Fixatives, France, Guidelines, HER2, Histological Techniques, Humans, Immunohistochemistry, Immunohistochimie, In Situ Hybridization, Prognosis, Receptor, ErbB-2, Receptors, Estrogen, Receptors, Progesterone, Receptors, Steroid, Recommandations, Specimen Handling
Date Added 2019/05/29 - 13:15:36
Date Modified 2019/05/29 - 13:15:48
Notes and Attachments PubMed entry (Attachment)


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