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Added by mollevi
Last modified by standudu
Group name EquipeVC
Item Type Journal Article
Title A consolidated method for screening the endocrine activity of drinking water
Creator Chevolleau et al.
Author S. Chevolleau
Author L. Debrauwer
Author T. Stroheker
Author L. Viglino
Author I. Mourahib
Author M. H. Meireles
Author M. Grimaldi
Author P. Balaguer
Author L. di Gioia
Abstract Endocrine activity of drinking water is a matter of growing interest for scientists as well as health authorities. A concentration technique for endocrine activity screening was developed, optimized, and transposed from 200mL to 10L water samples. To avoid any contamination during concentration, the method was developed using exclusively glass, Teflon and stainless steel materials. Any potential losses were tracked using three model radiolabeled molecules, namely BPA, DEHP and 4n-NP. The final method allowed 10L water samples to be concentrated 5000-fold, with good recovery and repeatability. After validation, by concentrating spiked and non-spiked 10L samples of EVIAN natural mineral water, 14 different drinking water samples were concentrated and screened for endocrine disrupting activity using bioluminescent assays. Samples consisting of bottled water, conditioned in various materials (glass, PET) and subjected to different storage conditions, had no hormone-like activities whereas estrogenic activity was found in the filtered tap water.
Publication Food Chem
Volume 213
Pages 274-83
Date Dec 15 2016
Journal Abbr Food chemistry
DOI 10.1016/j.foodchem.2016.06.089
ISSN 0308-8146 (Print) 0308-8146 (Linking)
Extra 00000
Tags original
Date Added 2018/11/14 - 12:10:52
Date Modified 2019/06/06 - 22:43:27
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27451182 (Attachment)


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