| Added by | Cavailles |
|---|---|
| Group name | EquipeVC |
| Item Type | Journal Article |
| Title | Regulation of intestinal homeostasis and tumorigenesis by the transcriptional coregulator RIP140 |
| Creator | Cavaillès and Lapierre |
| Author | Vincent Cavaillès |
| Author | Marion Lapierre |
| Abstract | Colon cancer frequently results from mutations that constitutively activate the Wnt signaling pathway, a major target being the tumor suppressor gene adenomatous polyposis coli (APC). We recently identified the transcription factor RIP140 as a new inducer of APC gene transcription that inhibits colon cancer cell growth and impedes the Wnt signaling pathway by reducing ?-catenin activation. |
| Publication | Molecular & Cellular Oncology |
| Volume | 1 |
| Issue | 2 |
| Pages | e960761 |
| Date | 2014 Apr-Jun |
| Journal Abbr | Mol Cell Oncol |
| Language | eng |
| DOI | 10.4161/23723548.2014.960761 |
| ISSN | 2372-3556 |
| Library Catalog | PubMed |
| Extra | PMID: 27308333 PMCID: PMC4905177 |
| Tags | APC, colon cancer, gut homeostasis, review, RIP140, Wnt signaling |
| Date Added | 2019/05/16 - 11:22:17 |
| Date Modified | 2019/05/16 - 11:33:25 |
| Notes and Attachments | PubMed entry (Attachment) Texte intégral (Attachment) |
Institut de Recherche en Cancérologie de
