Research
Epitranscriptomics & Cancer Adaptation : A.David

Activities

Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

More..

Zotero public

Added by André Pèlegrin
Group name EquipeAP
Item Type Journal Article
Title The Assisi Think Tank Meeting and Survey of post MAstectomy Radiation Therapy after breast reconstruction: The ATTM-SMART report
Creator Aristei et al.
Author Cynthia Aristei
Author Orit Kaidar-Person
Author Luca Tagliaferri
Author Meritxell Arenas
Author Charlotte E. Coles
Author Birgitte V. Offersen
Author Giovanni Frezza
Author Maria Cristina Leonardi
Author Vincenzo Valentini
Author Céline Bourgier
Author Philip M. P. Poortmans
Abstract PURPOSE: To describe the current European practise on post-mastectomy radiation therapy (PMRT) in relation to breast reconstruction. METHODS: A 21-item questionnaire was distributed online via Survey Monkey. Items referred to 1. general topics (country, centre, years of experience in breast cancer); 2. clinical decision making; 3. RT techniques and dosimetry; 4. dose fractionation. RESULTS: 283 responses were received from 19 countries. Most responders worked in public health services and in academic institutions and had 5-20 years experience. Although many indicated they were consulted about the timing and type of breast reconstructive surgery, final decisions were most often made by surgeons. Immediate reconstruction with expander followed by RT and subsequently permanent reconstruction with prosthesis was recommended by 61.6% of responders. Most (48.4%) adviced a boost only when margins were close or involved with an another 17.7% recommending it in the presence of high-risk features (T3-T4, lympho-vascular involvement). Intensity modulated RT was rarely used by about two-thirds of responders, except when with 3D technique the dose constraints were not achieved or when regional lymph nodes were included. Almost 60% of responders did not use bolus/tissue equivalent material (TEM). The main indication for bolus/TEM use was skin involvement. The majority of responders used 1.8-2 Gy per fraction. CONCLUSIONS: The present survey highlighted controversial areas in clinical practise, confirming the uncertainties about the scheduling of PMRT and breast reconstruction.
Publication European Journal of Surgical Oncology: The Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Volume 44
Issue 4
Pages 436-443
Date 04 2018
Journal Abbr Eur J Surg Oncol
Language eng
DOI 10.1016/j.ejso.2018.01.010
ISSN 1532-2157
Short Title The Assisi Think Tank Meeting and Survey of post MAstectomy Radiation Therapy after breast reconstruction
Library Catalog PubMed
Extra PMID: 29422254
Tags Breast Neoplasms, Breast reconstruction, clinic, Clinical Decision-Making, clinique hors équipe, Combined Modality Therapy, Congresses as Topic, Dose Fractionation, Female, Humans, Mammaplasty, Mastectomy, nonvisible, Post-mastectomy radiotherapy, Practice Patterns, Physicians', Radiotherapy Dosage, Survey, Surveys and Questionnaires, Time Factors
Date Added 2018/08/28 - 11:20:12
Date Modified 2019/12/11 - 18:20:00


© Institut de Recherche en Cancérologie de Montpellier - 2011 - Tous droits réservés - Mentions légales - Connexion - Conception : ID Alizés