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Epitranscriptomics & Cancer Adaptation : A.David

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Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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Added by mollevi
Group name EquipeMY
Item Type Journal Article
Title [Tumor banks and complex data management: Current and future challenges]
Creator Hofman et al.
Author Paul Hofman
Author Georges Dagher
Author Pierre Laurent-Puig
Author Charles Hugo-Marquette
Author Fabrice Barlesi
Author Frédéric Bibeau
Author Bruno Clément
Abstract Tumor banks are asked to clinical and translationnal research project development in oncology. They strongly participate to the assessment, then to the validation of diagnostic, prognostic and predictive biomarkers. The progressive change of these structures leads to induce a professionalization of their functioning and to identify them as key actors in oncology by the stakeholders of the public and private worlds. The progresses made in biotechnologies and therapeutics are rapidly modifying the impact and the proper functioning of the biobanks. These latter are now facing different challenges, in particular for their sustainability. Among the major issues, the integration of the clinical and biological data becoming increasingly complex leads to urgently consider an optimization of the role of different biobanks in France. Their goal is to be an attractive counterpart face to the international competition. The purpose of this review is to briefly describe the current evolution of the biobanks, then their present and future challenges, and finally the role made by the pathologists in these new issues in oncology field.
Publication Annales De Pathologie
Date Feb 25, 2019
Journal Abbr Ann Pathol
Language fre
DOI 10.1016/j.annpat.2019.01.017
ISSN 0242-6498
Short Title [Tumor banks and complex data management
Library Catalog PubMed
Extra PMID: 30819623
Tags Big data, Biobanks, Biobanque, Challenges, Data Management, Défis, Données massives, Forecasting, Humans, Neoplasms, Oncologie, Oncology, review, Tissue Banks
Date Added 2019/03/14 - 12:50:03
Date Modified 2020/01/28 - 09:50:12
Notes and Attachments PubMed entry (Attachment)
PubMed entry (Attachment)


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