| Added by | standudu |
|---|---|
| Group name | EquipeAT |
| Item Type | Journal Article |
| Title | First and repeat liver resection for primary and recurrent intrahepatic cholangiocarcinoma |
| Creator | Souche et al. |
| Author | Regis Souche |
| Author | Pietro Addeo |
| Author | Elie Oussoultzoglou |
| Author | Astrid Herrero |
| Author | Edoardo Rosso |
| Author | Francis Navarro |
| Author | Jean Michel Fabre |
| Author | Philippe Bachellier |
| Abstract | BACKGROUND: Recurrence after resection of intrahepatic cholangiocarcinoma (ICC) remains common. The present study sought to evaluate risk factors for recurrence and the results of repeat liver resection (RLR) for recurrent ICC. METHODS: Between 1997 and 2012, clinical data and outcomes of 125 consecutive patients undergoing liver resection for ICC were retrospectively analyzed. RESULTS: The rate of R0 resection was 89% (n = 110). Overall median survival was 35 months, and 1-, 3-, and 5-year actuarial survival rates were 80%, 48%, and 28%, respectively. Recurrence occurred in 76 patients (63.5%) and was intrahepatic only for 39 patients (51%). Tumor size greater than 5 cm was identified as an independent risk factor for recurrence (P ? .0001). RLR for recurrent ICC was feasible in 10 patients (25%) with a median survival after recurrence of 25 months (16 to 76). CONCLUSIONS: Tumor size more than 5 cm represents an independent risk factor for recurrence after resection of ICC. RLR in case of recurrent ICC, when feasible, is associated with longer overall survival. |
| Publication | American Journal of Surgery |
| Volume | 212 |
| Issue | 2 |
| Pages | 221-229 |
| Date | Aug 2016 |
| Journal Abbr | Am. J. Surg. |
| Language | eng |
| DOI | 10.1016/j.amjsurg.2015.07.016 |
| ISSN | 1879-1883 |
| Library Catalog | PubMed |
| Extra | PMID: 26552996 |
| Tags | Adult, Aged, Aged, 80 and over, Bile Duct Neoplasms, Cholangiocarcinoma, clinic, Female, Hepatectomy, Humans, Intrahepatic cholangiocarcinoma, Liver resection, Male, Middle Aged, Neoplasm Recurrence, Local, Recurrent cholangiocarcinoma, Reoperation, Repeat hepatectomy, Retrospective Studies, Risk Factors, Risk factors for recurrence, Survival, Survival Analysis |
| Date Added | 2019/05/29 - 14:23:32 |
| Date Modified | 2019/05/29 - 15:19:56 |
| Notes and Attachments | PubMed entry (Attachment) |
Institut de Recherche en Cancérologie de
