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Epitranscriptomics & Cancer Adaptation : A.David

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Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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Group name EquipeMY
Item Type Journal Article
Title [Should cases of hepatocellular carcinoma be discussed by non-specialized multidisciplinary team meetings?]
Creator Barbare et al.
Author J. C. Barbare
Author D. Franco
Author T. Andre
Author J. P. Bronowicki
Author P. Merle
Author J. M. Peron
Author J. L. Raoul
Author J. F. Seitz
Author M. Ychou
Abstract The treatment of hepatocellular carcinoma (HCC) is difficult due to the underlying cirrhosis which has its own influence on therapeutic issues. An inquiry was performed in centres with specialized multidisciplinary team meetings dedicated to HCC (HCC-MTM) or in centres with non-specialized (digestive oncology or general oncology) multidisciplinary team meetings (NS-MTM). The number of cases of HCCs taken in charge yearly was significantly higher in HCC-MTM than in NS-MTM (p=0,0014). Interventional radiologists and transplant surgeons were more frequently implied in HCC-MTM than in NS-MTM (respectively p=0,009 and p=0,02). On site availability of every treatment of HCC was higher in RCP-MTM than in NS-MTM (p=0,015). There were no inclusion in clinical trials in 40.5 % of NS-MTM versus only 17.6 % of HCC-MTM (p=0,0086). In three clinical cases out of seven there were discrepancies between the therapeutic options of HCC-MTM and NS-MTM. In all three cases, the treatment offered to the patient by HCC-MTM was more consistent with clinical standards. These results prompt to perform more studies on the quality of management of patients with HCCs by MTMs.
Publication Bull Cancer
Volume 101
Pages 558-63
Date Jun 2014
Journal Abbr Bulletin du cancer
DOI 10.1684/bdc.2014.1918
ISSN 1769-6917 (Electronic) 0007-4551 (Linking)
Tags *Interdisciplinary Communication, *Patient Care Team/statistics & numerical data, *Specialization, Carcinoma, Hepatocellular/*therapy, France, Health Care Surveys, Humans, Liver Neoplasms/*therapy, meeting, Patient Care Planning/statistics & numerical data
Date Added 2019/05/22 - 09:42:41
Date Modified 2019/05/22 - 09:45:58
Notes and Attachments (Note)
(Note)
24898934 (Attachment)


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