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Epitranscriptomics & Cancer Adaptation : A.David

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Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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Group name EquipeCTCS
Item Type Journal Article
Title Robotic Versus Laparoscopic Total Mesorectal Excision for Sphincter-Saving Surgery: Results of a Single-Center Series of 400 Consecutive Patients and Perspectives
Creator Rouanet et al.
Author Philippe Rouanet
Author Martin Marie Bertrand
Author Marta Jarlier
Author Anne Mourregot
Author Drissa Traore
Author Christophe Taoum
Author Hélène de Forges
Author Pierre-Emmanuel Colombo
Abstract OBJECTIVE: The aim of this study is to compare robotic total mesorectal excision (R-TME) with laparoscopic TME (L-TME) in a series of consecutive rectal cancer patients. BACKGROUND: R-TME and L-TME have drawn contradictory reports. A recent phase III trial (ROLARR) concluded that R-TME performed by surgeons with varying experience did not confer an advantage in rectal cancer resection. PATIENTS AND METHODS: In this retrospective single-center cohort study (8/2008 to 4/2015), data were prospectively registered. A total of 200 L-TME and 200 R-TME were operated consecutively without selection. The primary outcome was the conversion rate to open laparotomy or transanal TME. The secondary endpoints were type of anastomosis, operative time, postoperative morbidity, circumferential radial (CRM) and distal margins, quality of life, bladder and sexual dysfunction, and oncological outcomes. RESULTS: Baseline characteristics were well balanced. Type of anastomosis [colo-anal anastomosis (CAA) 40% vs 49%; p?
Publication Annals of Surgical Oncology
Volume 25
Issue 12
Pages 3572-3579
Date Nov 2018
Journal Abbr Ann. Surg. Oncol.
Language eng
DOI 10.1245/s10434-018-6738-5
ISSN 1534-4681
Short Title Robotic Versus Laparoscopic Total Mesorectal Excision for Sphincter-Saving Surgery
Library Catalog PubMed
Extra PMID: 30171509
Tags clinic, stan
Date Added 2018/11/14 - 15:24:24
Date Modified 2019/05/14 - 20:03:10
Notes and Attachments PubMed entry (Attachment)


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