| Added by | André Pèlegrin |
|---|---|
| Group name | EquipeAP |
| Item Type | Journal Article |
| Title | [Predictive assays for responses of tumors and normal tissues in radiation oncology] |
| Creator | Riou et al. |
| Author | O. Riou |
| Author | C. Bourgier |
| Author | M. Brengues |
| Author | N. Bonnefoi |
| Author | H.-A. Michaud |
| Author | F. Castan |
| Author | S. Gourgou |
| Author | R. Draghici |
| Author | M.-P. Farcy-Jacquet |
| Author | F. Bons |
| Author | P. Fenoglietto |
| Author | M. Ozsahin |
| Author | D. Azria |
| Abstract | The impact of curative radiotherapy depends mainly on the total dose delivered homogenously in the target volume. Tumor sensitivity to radiotherapy may be particularly inconstant depending on location, histology, somatic genetic parameters and the capacity of the immune system to infiltrate the tumor. In addition, the dose delivered to the surrounding healthy tissues may reduce the therapeutic ratio of many radiation treatments. In a same population treated in one center with the same technique, it appears that individual radiosensitivity clearly exists, namely in terms of late side effects that are in principle non-reversible. This review details the different radiobiological approaches that have been developed to better predict the tumor response but also the radiation-induced late effects. |
| Publication | Cancer Radiotherapie: Journal De La Societe Francaise De Radiotherapie Oncologique |
| Date | Aug 23, 2019 |
| Journal Abbr | Cancer Radiother |
| Language | fre |
| DOI | 10.1016/j.canrad.2019.07.152 |
| ISSN | 1769-6658 |
| Library Catalog | PubMed |
| Extra | 00000 PMID: 31451357 |
| Tags | nonvisible, Normal tissue, Predictive assay, Radiothérapie, Radiotherapy, review, Test radiosensibilité, Tissu sain, Tumeur, Tumor |
| Date Added | 2019/09/12 - 09:49:47 |
| Date Modified | 2019/12/11 - 18:33:50 |
| Notes and Attachments | PubMed entry (Attachment) |
Institut de Recherche en Cancérologie de
