| Added by | Nathalie Bonnefoy |
|---|---|
| Group name | EquipeNB |
| Item Type | Journal Article |
| Title | Evaluation of response after SBRT for liver tumors |
| Creator | Tétreau et al. |
| Author | Carmen Llacer |
| Author | Olivier Riou |
| Author | Emmanuel Deshayes |
| Abstract | Stereotactic body radiotherapy (SBRT) has developed over the last few years for the treatment of primary and metastatic hepatic tumors. The tumoral and adjacent peritumoral modifications caused by this radiosurgery limit the evaluation of response by anatomic imaging and dimensional criteria alone, such as with RECIST. This suggests that it is of interest to also take into account the residual enhancement and hyper metabolism of these hepatic targets. We have reviewed the English language literature regarding the response of hepatic lesions treated by SBRT, and found that only seven articles were specifically concerned with this problem. The response of the hepatocellular carcinoma after SBRT has been studied specifically with multiphase enhanced CT-scan. Criteria set by the European Association of Study of the Liver better estimate response at each time point of follow up than RECIST does. Non-enhancement, reflecting tumor necrosis, is additionally an early indicator of response with extended response in time and a best non-enhancement percentage is observed at 12 months. The response after treatment by SBRT of cholangiocarcinoma has not yet generated a specific report. Use of RECIST criteria is also inadequate in the evaluation of response after SBRT for hepatic metastases. Response of liver metastases to SBRT is better assessed with a combination of size and enhancement pattern. The occurrence of a lobulated enhancement during follow up is efficient to predict local progression in a specific, reproducible, and sensitive way. Patients with FDG-avid hepatic metastases are also better evaluated with PET-CT and functional criteria than routine imaging and metric evaluation alone. |
| Publication | Reports of Practical Oncology and Radiotherapy: Journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology |
| Volume | 22 |
| Issue | 2 |
| Pages | 170-175 |
| Date | 2017 Mar-Apr |
| Journal Abbr | Rep Pract Oncol Radiother |
| Language | eng |
| DOI | 10.1016/j.rpor.2015.12.004 |
| ISSN | 1507-1367 |
| Library Catalog | PubMed |
| Extra | PMID: 28490989 PMCID: PMC5411810 |
| Tags | CT, computerized tomography, EASL, European Association of Study of the Liver, FDG, fluorodeoxyglucose, HCC, Hepatocellular carcinoma, Liver, mRECIST, modified criteria of response in solid tumors, MRI, magnetic resonance imaging, PERCIST, PET Response Criteria in Solid Tumors, PET, positron-emission tomography, RECIST, criteria of response in solid tumors, review, SBRT, stereotactic body radiotherapy, Stereotactic body radiotherapy, SUV, standard uptake value, Tomography, Treatment effectiveness, X-ray computed |
| Date Added | 2019/05/28 - 21:41:26 |
| Date Modified | 2019/05/28 - 21:42:01 |
| Notes and Attachments | PubMed entry (Attachment) Texte intégral (Attachment) |
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