| Added by | celine.gongora |
|---|---|
| Group name | EquipeCG |
| Item Type | Journal Article |
| Title | [Immunotherapy in urology: Concept and results] |
| Creator | Pignot and Houede |
| Author | G. Pignot |
| Author | N. Houede |
| Abstract | OBJECTIVE: The purpose of this article is to update current data on immunotherapy in uro-oncology. MATERIAL AND METHODS: Synthesis of data from recent literature and data presented at national and international conferences on immunotherapy in urological cancers. RESULTS: Current immunotherapies restore the anti-tumor immunity, by blocking immunity-negative feedback checkpoints. In metastatic renal cell carcinoma and bladder carcinoma, immunotherapy has first shown a significant survival benefit in second-line, and more recently in first-line for kidney cancer. Trials are currently ongoing in adjuvant and neoadjuvant settings. In prostate cancer, there is little data and immunotherapy seems to benefit a limited subgroup of patients. CONCLUSION: Immunotherapy is a key treatment in kidney and bladder cancer. In the future, the identification of predictive markers should allow us to better select patients responding to immunotherapy. |
| Publication | Progres En Urologie: Journal De l'Association Francaise D'urologie Et De La Societe Francaise D'urologie |
| Date | Aug 30, 2019 |
| Journal Abbr | Prog. Urol. |
| Language | fre |
| DOI | 10.1016/j.purol.2019.08.267 |
| ISSN | 1166-7087 |
| Short Title | [Immunotherapy in urology |
| Library Catalog | PubMed |
| Extra | 00000 PMID: 31477432 |
| Tags | last, review |
| Date Added | 2019/10/10 - 10:42:23 |
| Date Modified | 2019/10/24 - 17:23:47 |
| Notes and Attachments | PubMed entry (Attachment) |
Institut de Recherche en Cancérologie de
