| Added by | JPPOUGET |
|---|---|
| Group name | EquipeJPP |
| Item Type | Journal Article |
| Title | LYMPHOSCORE (Lymphoscintigraphy Scoring Reliability) Reliability of a New Qualitative and Semiquantitative Lymphoscintigraphy Scoring System for Primary Lymphedema |
| Creator | Guillemard et al. |
| Author | Sophie Guillemard |
| Author | Lionel Moulis |
| Author | Diana Ilonca |
| Author | Sandrine Mestre |
| Author | Emmanuel Deshayes |
| Author | Isabelle Quéré |
| Author | Salma Adham |
| Abstract | PURPOSE OF THE REPORT: Primary lymphedema (PLE) is a rare chronic disorder. Extremity lymphoscintigraphy offers access for dynamic and functional information on peripheral lymphatics and lymph nodes. We aimed to assess intraobserver and interobserver reliability of a new lymphoscintigraphy quantitative and qualitative scoring system in a homogeneous population of adult patients followed for PLE of the lower limb(s). PATIENTS AND METHODS: This is a monocentric retrospective study. Clinical files of patients who underwent a lymphoscintigraphy were reviewed for inclusion. Lymphoscintigraphies were interpreted twice by 2 observers with a washout period. To assess intraobserver and interobserver reliability for both lower limbs, Cohen ? and Gwet's AC1 reliability coefficients were calculated with 95% confidence interval and P value of the zero-reliability comparison test. To interpret reliability coefficients, we used the orders of magnitude reported by Landis and Koch. RESULTS: One hundred forty-four patients (288 limbs) with PLE were included. For intraobserver reliability, agreement range was 0.87-1 with an almost perfect agreement in all staging items of the score for both limbs with the lower limit of the 95% confidence interval ?80%. Interobserver reliability was overall strong or almost perfect, ranging from 0.67 to 0.97. CONCLUSIONS: This new scoring system demonstrated excellent intraobserver reliability and a very good interobserver reliability. Lymphoscintigraphy, when performed in a referral center and interpreted by trained nuclear medicine physicians, is a reliable means of investigation in patients with PLE of the lower limbs. This reproducibility advocates for further use of lymphoscintigraphy in multicentric cohorts of PLE patients. |
| Publication | Clinical Nuclear Medicine |
| Volume | 49 |
| Issue | 9 |
| Pages | e428-e435 |
| Date | 2024-09-01 |
| Journal Abbr | Clin Nucl Med |
| Language | eng |
| DOI | 10.1097/RLU.0000000000005357 |
| ISSN | 1536-0229 |
| Library Catalog | PubMed |
| Extra | PMID: 38915154 |
| Tags | Adult, Aged, Aged, 80 and over, clinic, Female, Humans, Lymphedema, Lymphoscintigraphy, Male, Middle Aged, Observer Variation, Reproducibility of Results, Retrospective Studies |
| Date Added | 2024/12/07 - 07:57:39 |
| Date Modified | 2024/12/15 - 11:16:49 |
| Notes and Attachments | PubMed entry (Attachment) PubMed entry (Attachment) PubMed entry (Attachment) PubMed entry (Attachment) PubMed entry (Attachment) PubMed entry (Attachment) PubMed entry (Attachment) PubMed entry (Attachment) PubMed entry (Attachment) PubMed entry (Attachment) PubMed entry (Attachment) |
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