| Added by | JPPOUGET |
|---|---|
| Group name | EquipeJPP |
| Item Type | Journal Article |
| Title | Recommendations for planning and delivery of radical radiotherapy for localized urothelial carcinoma of the bladder |
| Creator | Khalifa et al. |
| Author | Jonathan Khalifa |
| Author | Stéphane Supiot |
| Author | Géraldine Pignot |
| Author | Christophe Hennequin |
| Author | Pierre Blanchard |
| Author | David Pasquier |
| Author | Renaud de Crevoisier |
| Author | Pierre Graff-Cailleaud |
| Author | Olivier Riou |
| Author | Morgane Cabaillé |
| Author | David Azria |
| Author | Igor Latorzeff |
| Author | Gilles Créhange |
| Author | Olivier Chapet |
| Author | Morgan Rouprêt |
| Author | Sarah Belhomme |
| Author | Paul Sargos |
| Abstract | PURPOSE: Curative radio-chemotherapy is recognized as a standard treatment option for muscle-invasive bladder cancer (MIBC). Nevertheless, the technical aspects for MIBC radiotherapy are heterogeneous with a lack of practical recommendations. METHODS AND MATERIALS: In 2018, a workshop identified the need for two cooperative groups to develop consistent, evidence-based guidelines for irradiation technique in the delivery of curative radiotherapy. Two radiation oncologists performed a review of the literature addressing several topics relative to radical bladder radiotherapy: planning computed tomography acquisition, target volume delineation, radiation schedules (total dose and fractionation) and dose delivery (including radiotherapy techniques, image-guided radiotherapy (IGRT) and adaptive treatment modalities). Searches for original and review articles in the PubMed and Google Scholar databases were conducted from January 1990 until March 2020. During a meeting conducted in October 2020, results on 32 topics were presented and discussed with a working group involving 15 radiation oncologists, 3 urologists and one medical oncologist. We applied the American Urological Association guideline development's method to define a consensus strategy. RESULTS: A consensus was obtained for all 34 except 4 items. The group did not obtain an agreement on CT enhancement added value for planning, PTV margins definition for empty bladder and full bladder protocols, and for pelvic lymph-nodes irradiation. High quality evidence was shown in 6 items; 8 items were considered as low quality of evidence. CONCLUSION: The current recommendations propose a homogenized modality of treatment both for routine clinical practice and for future clinical trials, following the best evidence to date, analyzed with a robust methodology. The XXX group formulates practical guidelines for the implementation of innovative techniques such as adaptive radiotherapy. |
| Publication | Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology |
| Volume | 161 |
| Pages | 95-114 |
| Date | 2021-08 |
| Journal Abbr | Radiother Oncol |
| Language | eng |
| DOI | 10.1016/j.radonc.2021.06.011 |
| ISSN | 1879-0887 |
| Library Catalog | PubMed |
| Extra | PMID: 34118357 |
| Tags | Bladder cancer, Carcinoma, Transitional Cell, clinic, Guidelines, Humans, Image guided radiation therapy, Radiotherapy, Radiotherapy Dosage, Radiotherapy Planning, Computer-Assisted, Radiotherapy, Image-Guided, Radiotherapy, Intensity-Modulated, Trimodal therapy, Urinary Bladder Neoplasms |
| Date Added | 2023/11/23 - 12:48:32 |
| Date Modified | 2024/12/15 - 11:26:05 |
| Notes and Attachments | PubMed entry (Attachment) Texte intégral (Attachment) |
Institut de Recherche en Cancérologie de
