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Epitranscriptomics & Cancer Adaptation : A.David

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Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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Added by André Pèlegrin
Group name EquipeAP
Item Type Journal Article
Title Personalizing Breast Cancer Irradiation Using Biology: From Bench to the Accelerator
Creator Azria et al.
Author David Azria
Author Muriel Brengues
Author Sophie Gourgou
Abstract While adjuvant treatments of early breast cancers (BCs) had significantly improved patients' overall survival, some of them will still develop locoregional relapses and/or severe late radio-induced toxicities. Here, we propose to review how to personalize locoregional treatment by identifying patients at high and low risk of locoregional relapse, patients at risk of late radio-induced side effects. We will, therefore, discuss how to enhance BC radiosensitivity. Finally, we will address how personalized radiotherapy could be implemented in prospective clinical trials.
Publication Frontiers in Oncology
Volume 8
Pages 83
Date 2018
Journal Abbr Front Oncol
Language eng
DOI 10.3389/fonc.2018.00083
ISSN 2234-943X
Short Title Personalizing Breast Cancer Irradiation Using Biology
Library Catalog PubMed
Extra PMID: 29675397 PMCID: PMC5895767
Tags breast cancer, Equipe, normal tissue complications, radiosensitization, review, Revue
Date Added 2018/08/28 - 11:20:03
Date Modified 2019/05/14 - 12:17:29


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