| Added by | adjiane.lab |
|---|---|
| Group name | EquipeAD |
| Item Type | Journal Article |
| Title | Factitious hypoglycemia in insulin-treated diabetic patients |
| Creator | Galvez et al. |
| Author | Thierry Galvez |
| Author | Manuela Lotierzo |
| Author | Guilhem Conquet |
| Author | Quentin Verani |
| Author | Caroline Aguilhon |
| Author | Isabelle Raingeard |
| Author | Jean-Paul Cristol |
| Author | Eric Renard |
| Abstract | Factitious hypoglycemia is a factitious disorder according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), referring to intentionally covertly induced hypoglycemia, with potentially severe consequences. Knowledge of factitious hypoglycemia relies on case reports, and evidence-based information and guidelines are lacking. Diagnosing factitious hypoglycemia in insulin-treated diabetic persons is therefore challenging and often requires a long and costly process. Moreover, the typical metrics proposed to differentiate insulin-induced factitious hypoglycemia from insulinoma (i.e., high insulin and low C-peptide versus high insulin and high C-peptide, respectively) are not always applicable, depending on whether the insulin quantification method can detect the insulin analog. When factitious hypoglycemia is suspected, an emerging trend from recent publications advocates a combination of two insulin quantification methods with different cross-reactivity for insulin analogs, early on in the diagnostic process. |
| Publication | Annales D'endocrinologie |
| Volume | 84 |
| Issue | 3 |
| Pages | 364-366 |
| Date | 2023-05 |
| Journal Abbr | Ann Endocrinol (Paris) |
| Language | eng |
| DOI | 10.1016/j.ando.2023.03.015 |
| ISSN | 2213-3941 |
| Library Catalog | PubMed |
| Extra | PMID: 36965853 |
| Tags | C-Peptide, clinic, Diabetes Mellitus, Factitious disorder, Factitious Disorders, first, Humans, Hypoglycemia, Insulin, Insulin quantification immunoassay, Munchausen syndrome, Pancreatic Neoplasms |
| Date Added | 2024/09/30 - 01:25:21 |
| Date Modified | 2024/09/30 - 18:17:57 |
| Notes and Attachments | PubMed entry (Attachment) PubMed entry (Attachment) Submitted Version (Attachment) |
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