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Epitranscriptomics & Cancer Adaptation : A.David

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Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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Added by adjiane.lab
Group name EquipeAD
Item Type Journal Article
Title [Drosophila as a model to study cancer biology]
Creator Falconi et al.
Author Jennifer Falconi
Author Katrin Strobel
Author Alexandre Djiane
Author Patrice Lassus
Abstract The rising global incidence of cancer makes it the second leading cause of death worldwide. Over the past decades, significant progress has been made in both basic knowledge and the discovery of new therapeutic approaches. However, the complexity of mechanisms related to tumor development requires the use of sophisticated and adapted research tools. Among these, the fruitfly Drosophila melanogaster represents a powerful genetic model with numerous practical and conceptual advantages. Indeed, the conservation of genes implicated in cancer between this insect and mammals places Drosophila as a crucial genetic tool for understanding the fundamental mechanisms governing tumorigenesis and identifying new therapeutic targets. This review aims to describe this original model and demonstrate its relevance for studying cancer biology.
Publication Bulletin Du Cancer
Volume 111
Issue 9
Pages 880-892
Date 2024-09
Journal Abbr Bull Cancer
Language fre
DOI 10.1016/j.bulcan.2024.05.005
ISSN 1769-6917
Library Catalog PubMed
Extra PMID: 38960821
Tags Animals, anr, arc, Carcinogenesis, Disease Models, Animal, Drosophila, Drosophila melanogaster, Drosophile, first-last-corresponding, Génétique, gso, ligue, Model, Modèle, Neoplasms, phd, review, siric
Date Added 2024/09/30 - 01:09:59
Date Modified 2024/09/30 - 18:13:35
Notes and Attachments PubMed entry (Attachment)


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