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Epitranscriptomics & Cancer Adaptation : A.David

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Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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Added by mollevi
Last modified by pcoopman
Group name EquipePC
Item Type Journal Article
Title Late side-effects after curative intent radiotherapy: Identification of hypersensitive patients for personalized strategy
Creator Bourgier et al.
Author C. Bourgier
Author J. Lacombe
Author J. Solassol
Author A. Mange
Author A. Pelegrin
Author M. Ozsahin
Author D. Azria
Abstract Radiation therapy undeniably enhances local control and thus improves overall survival in cancer patients. However, some long-term cancer survivors (less than 10%) develop severe late radio-induced toxicities altering their quality of life. Therefore, there is a need to identify patients who are sensitive to those toxicities and who could benefit from adapted care. In this review, we address all available techniques aiming to detect patients' hyper-radiosensitivity and present the scientific rationales these techniques are based on.
Publication Crit Rev Oncol Hematol
Volume 93
Pages 312-9
Date Mar 2015
Journal Abbr Critical reviews in oncology/hematology
DOI 10.1016/j.critrevonc.2014.11.004
ISSN 1879-0461 (Electronic) 1040-8428 (Linking)
Tags *Radiation Injuries/diagnosis, *Survivors, Biological Markers, Individualized Medicine, Neoplasms/*complications/mortality/radiotherapy, Prognosis, Radiation Tolerance, Radiotherapy/*adverse effects, review, Risk Factors, Time Factors, Treatment Outcome
Date Added 2018/11/14 - 12:07:50
Date Modified 2019/05/16 - 15:57:29
Notes and Attachments (Note)
(Note)
25497158 (Attachment)


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