| Added by | pmartino |
|---|---|
| Group name | EquipePM |
| Item Type | Journal Article |
| Title | [Contribution of intraperitoneal chemotherapy in the treatment of colorectal peritoneal carcinoma. HIPEC, PIPAC, state of the art and future directions] |
| Creator | Quénet et al. |
| Author | François Quénet |
| Author | Sébastien Carrère |
| Author | Olivia Sgarbura |
| Abstract | After more than a decade of good results using the combination of cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) in the treatment of peritoneal carcinosis of colorectal origin, the PRODIGE7 study, which specifically evaluated the role of HIPEC, failed to show any superiority in terms of overall and disease-free survival for the CRS+HIPEC combination compared with CRS alone. This study constituted a radical change in the knowledge and therapeutic attitudes observed to date. After reviewing the literature and the consensus of national and international experts, a synthesis is provided, together with an outlook on the questions raised and the therapeutic trials and innovations of the near future. An analysis of recent advances due to the advent of a new technique, PIPAC, is also proposed, as well as a review of current therapeutic trials in this field. |
| Publication | Bulletin Du Cancer |
| Volume | 111 |
| Issue | 3 |
| Pages | 285-290 |
| Date | 2024-03 |
| Journal Abbr | Bull Cancer |
| Language | fre |
| DOI | 10.1016/j.bulcan.2023.10.006 |
| ISSN | 1769-6917 |
| Library Catalog | PubMed |
| Extra | PMID: 38331695 |
| Tags | Antineoplastic Combined Chemotherapy Protocols, Cancer colorectal, Carcinoma, Carcinose péritonéale, Chemotherapy, Cancer, Regional Perfusion, CHIP, Chirurgie de cytoréduction, clinic, Colorectal Neoplasms, Combined Modality Therapy, Cytoreductive surgery, first, HIPEC, Humans, Hyperthermia, Induced, Peritoneal Neoplasms, PIPAC, Survival Rate |
| Date Added | 2024/08/02 - 09:53:13 |
| Date Modified | 2024/08/02 - 10:00:55 |
| Notes and Attachments | PubMed entry (Attachment) |
Institut de Recherche en Cancérologie de
