| Added by | standudu |
|---|---|
| Group name | EquipeCTCS |
| Item Type | Journal Article |
| Title | Changes in vitamin D and calcium metabolism markers in patients undergoing adjuvant chemotherapy for breast cancer |
| Creator | Viala et al. |
| Author | Marie Viala |
| Author | Nelly Firmin |
| Author | Célia Touraine |
| Author | Manon Metge |
| Author | Lobna Rifai |
| Author | Gilles Romieu |
| Author | Hélène de Forges |
| Author | Lise Roca |
| Author | Séverine Guiu |
| Author | Véronique D'Hondt |
| Author | William Jacot |
| Abstract | BACKGROUND: Changes in calcium metabolism and calcium urinary excretion during chemotherapy have not been thoroughly assessed in patients with early breast cancer (EBC), a population who frequently present vitamin D insufficiency. As hypercalciuria is a classical contra-indication to vitamin D (VD) supplementation, this study evaluated changes in VD and calcium metabolism parameters in patients with EBC undergoing adjuvant chemotherapy (CT). METHODS: In patients with EBC who received six cycles of adjuvant CT, VD and calcium parameters were monitored at inclusion, and then every 3?weeks, at each CT cycle initiation. The primary endpoint was the percentage of patients showing hypercalciuria during adjuvant CT (between Day 1, Cycle 1 [D1C1] and Day 1, Cycle 6 [D1C6]). RESULTS: The primary endpoint could be evaluated in 82 patients. Most patients (n?=?66, 80.5%) had VD insufficiency ( |
| Publication | BMC cancer |
| Volume | 21 |
| Issue | 1 |
| Pages | 815 |
| Date | 2021-07-15 |
| Journal Abbr | BMC Cancer |
| Language | eng |
| DOI | 10.1186/s12885-021-08563-4 |
| ISSN | 1471-2407 |
| Library Catalog | PubMed |
| Extra | PMID: 34266398 PMCID: PMC8283899 |
| Tags | Adjuvant chemotherapy, Adult, Aged, Breast Neoplasms, Calcium, corresponding, Female, first-last-corresponding, Humans, Hypercalciuria, last, marque, Middle Aged, original, Vitamin D, Young Adult |
| Date Added | 2022/07/29 - 15:45:01 |
| Date Modified | 2022/08/01 - 16:19:19 |
| Notes and Attachments | PubMed entry (Attachment) Texte intégral (Attachment) |
Institut de Recherche en Cancérologie de
