| Added by | adjiane.lab |
|---|---|
| Group name | EquipeAD |
| Item Type | Journal Article |
| Title | Head and neck cancer patients treated with concomitant chemoradiotherapy involving the oral cavity and oropharynx: is another choice possible than prophylactic gastrostomy? |
| Creator | Senesse et al. |
| Author | Pierre Senesse |
| Author | Jeanne Briant |
| Author | Pierre Boisselier |
| Author | René-Jean Bensadoun |
| Author | Marie Vinches |
| Author | Kerstin Faravel |
| Abstract | PURPOSE OF REVIEW: Recent recommendations on cachexia highlight, in head and neck cancers, the heterogeneity of studies, focusing on weight loss and sequelae including swallowing disorders. The current national guidelines emphasize that, in cases of concurrent chemoradiotherapy (cCRT) involving the oral cavity and oropharynx, prophylactic gastrostomy placement should be carried out systematically. We review why this technique is particularly relevant in this specific location for the feasibility of cCRT. RECENT FINDINGS: A randomized trial is underway on swallowing disorders and the quality of life of patients after prophylactic vs. reactive gastrostomy in advanced oropharyngeal cancer patients treated with CRT. Concurrently, recent literature reviews emphasize the importance of the cumulative dose of chemotherapy for local control and survival. In cases of cCRT involving the oral cavity or the oropharynx, nutritional support could have a beneficial or detrimental impact on chemotherapy. SUMMARY: Specifically for patients treated with cCRT involving the oral cavity and oropharynx, prophylactic gastrostomy would be able to fulfill the three objectives of local control, survival, and quality of life, minimizing complications related to nutritional support. Studies need to be more homogeneous. In clinical practice, nutrition should primarily assist in carrying out cancer treatment when survival is the main goal. |
| Publication | Current Opinion in Oncology |
| Volume | 36 |
| Issue | 3 |
| Pages | 128-135 |
| Date | 2024-05-01 |
| Journal Abbr | Curr Opin Oncol |
| Language | eng |
| DOI | 10.1097/CCO.0000000000001031 |
| ISSN | 1531-703X |
| Short Title | Head and neck cancer patients treated with concomitant chemoradiotherapy involving the oral cavity and oropharynx |
| Library Catalog | PubMed |
| Extra | PMID: 38573201 |
| Tags | Chemoradiotherapy, clinic, Deglutition Disorders, first, Gastrostomy, Head and Neck Neoplasms, Humans, Mouth, Oropharynx, Quality of Life, Randomized Controlled Trials as Topic |
| Date Added | 2024/09/30 - 01:13:05 |
| Date Modified | 2024/09/30 - 18:17:18 |
| Notes and Attachments | PubMed entry (Attachment) |
Institut de Recherche en Cancérologie de
