Research
Epitranscriptomics & Cancer Adaptation : A.David

Activities

Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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Title  Creator  Group name  Publishing year 
[A new generation of immunotherapies targeting the CD39/CD73/adenosine pathway to promote the anti-tumor immune response] Gros et al. EquipeNB Feb 2020
Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies Perrot et al. EquipeNB May 21, 2019
Increased degradation of ATP is driven by memory regulatory T cells in kidney transplantation tolerance Durand et al. EquipeNB 05 2018
The IL-17B-IL-17 receptor B pathway promotes resistance to paclitaxel in breast tumors through activation of the ERK1/2 pathway Laprevotte et al. EquipeCTCS Dec 26, 2017
PD-1 blockade at the time of tumor escape potentiates the immune-mediated antitumor effects of a melanoma-targeting monoclonal antibody They et al. EquipeNB 2017
IL-21 promotes the development of a CD73-positive V?9V?2 T cell regulatory population Barjon et al. EquipeEJ 2017
Inhibition of CD39 enzymatic function at the surface of tumor cells alleviates their immunosuppressive activity Bastid et al. PlateformePP2I Mar 2015
Comprehensive characterization of immunoglobulin gene rearrangements in patients with chronic lymphocytic leukaemia René et al. EquipeNB Jun 2014


© Institut de Recherche en Cancérologie de Montpellier - 2011 - Tous droits réservés - Mentions légales - Connexion - Conception : ID Alizés