Research
Epitranscriptomics & Cancer Adaptation : A.David

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Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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8 Items
Title  Creator  Group name  Publishing year 
The mechanosensitive TRPV2 calcium channel promotes human melanoma invasiveness and metastatic potential Shoji et al. EquipeELC 2023-02-06
Secretion of IL1 by Dedifferentiated Melanoma Cells Inhibits JAK1-STAT3-Driven Actomyosin Contractility of Lymph Node Fibroblastic Reticular Cells Rovera et al. EquipeELC 2022-05-03
Targeting Discoidin Domain Receptors DDR1 and DDR2 overcomes matrix-mediated tumor cell adaptation and tolerance to BRAF-targeted therapy in melanoma Berestjuk et al. EquipeELC 2021-12-27
A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment Alcaraz et al. EquipeCTCS 2021
A Feed-Forward Mechanosignaling Loop Confers Resistance to Therapies Targeting the MAPK Pathway in BRAF-Mutant Melanoma Girard et al. EquipeELC 2020-05-15
Targeting the Proteasome-Associated Deubiquitinating Enzyme USP14 Impairs Melanoma Cell Survival and Overcomes Resistance to MAPK-Targeting Therapies Didier et al. EquipeELC Jul 2018
Tumour-derived SPARC drives vascular permeability and extravasation through endothelial VCAM1 signalling to promote metastasis Tichet et al. EquipeELC Apr 30, 2015
Cherubism allele heterozygosity amplifies microbe-induced inflammatory responses in murine macrophages Prod'Homme et al. EquipeELC Apr 2015
8 Items


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Located in the Parc Euromédecine, the Institut de Recherche en Cancérologie de Montpellier (U1194) is located on the Val d'Aurelle Campus (ICM, Institut régional du Cancer Montpellier/ Val d'Aurelle).

U1194 Research Centre supported by Inserm, the University of Montpellier and the Institut du Cancer de Montpellier (ICM)

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Montpellier (U1194) - Campus Val d'Aurelle

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