Research
Epitranscriptomics & Cancer Adaptation : A.David

Activities

Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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Title  Creator  Group name  Publishing year 
Secretion of IL1 by Dedifferentiated Melanoma Cells Inhibits JAK1-STAT3-Driven Actomyosin Contractility of Lymph Node Fibroblastic Reticular Cells Rovera et al. EquipeELC 2022-05-03
Targeting Discoidin Domain Receptors DDR1 and DDR2 overcomes matrix-mediated tumor cell adaptation and tolerance to BRAF-targeted therapy in melanoma Berestjuk et al. EquipeELC 2021-12-27
Comparison of SYK Signaling Networks Reveals the Potential Molecular Determinants of Its Tumor-Promoting and Suppressing Functions Buffard et al. EquipePC 2021-02-18
A Feed-Forward Mechanosignaling Loop Confers Resistance to Therapies Targeting the MAPK Pathway in BRAF-Mutant Melanoma Girard et al. EquipeELC 2020-05-15
Targeting the Proteasome-Associated Deubiquitinating Enzyme USP14 Impairs Melanoma Cell Survival and Overcomes Resistance to MAPK-Targeting Therapies Didier et al. EquipeELC Jul 2018
BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic mice Hamouda et al. EquipeELC 08 22, 2016
Tumour-derived SPARC drives vascular permeability and extravasation through endothelial VCAM1 signalling to promote metastasis Tichet et al. EquipeELC Apr 30, 2015
Cherubism allele heterozygosity amplifies microbe-induced inflammatory responses in murine macrophages Prod'Homme et al. EquipeELC Apr 2015
Forkhead box O3 (FOXO3) transcription factor mediates apoptosis in BCG-infected macrophages Haoues et al. EquipeELC Sep 2014


© Institut de Recherche en Cancérologie de Montpellier - 2011 - Tous droits réservés - Mentions légales - Connexion - Conception : ID Alizés