Research
Epitranscriptomics & Cancer Adaptation : A.David

Activities

Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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37 Items
Title  Creator  Group name  Publishing year 
Discovery of a pan anti-SARS-CoV-2 monoclonal antibody with highly efficient infected cell killing capacity for novel immunotherapeutic approaches Abba Moussa et al. EquipePM 2025-12
Identification of monoclonal antibodies from naive antibody phage-display libraries for protein detection in formalin-fixed paraffin-embedded tissues Mairaville et al. EquipePM 2024-07-25
Generation of non-genetically modified, CAR-like, NK cells Coënon et al. EquipePM 2024-07-18
A novel Fc-engineered cathepsin D-targeting antibody enhances ADCC, triggers tumor-infiltrating NK cell recruitment, and improves treatment with paclitaxel and enzalutamide in triple-negative breast cancer Desroys du Roure et al. EquipePM 2024-01-30
Novel trehalose-based excipients for stabilizing nebulized anti-SARS-CoV-2 antibody Noverraz et al. EquipePM 2023-01-05
Fc-engineered monoclonal antibodies to reduce off-target liver uptake Mangeat et al. EquipeJPP 2023-09-11
Anti-cathepsin D immunotherapy triggers both innate and adaptive anti-tumour immunity in breast cancer David et al. EquipePM 2023-11-29
Activation of neuronal FLT3 promotes exaggerated sensorial and emotional pain-related behaviors facilitating the transition from acute to chronic pain Tassou et al. EquipePM 2023-01-13
A bioinspired approach for the modulation of electroosmotic flow and protein-surface interactions in capillary electrophoresis using silylated amino-amides blocks and covalent grafting Gouyon et al. PlateformePP2I 2023-12-31
10th antibody industrial symposium: new developments in antibody and adoptive cell therapies Antunes et al. EquipePM 2023
Targeting the splicing isoforms of spleen tyrosine kinase affects the viability of colorectal cancer cells Denis et al. PlateformePP2I 2022
Oncogenic Signalling of PEAK2 Pseudokinase in Colon Cancer Lecointre et al. EquipePM 2022-06-16
The NANOTUMOR consortium - Towards the Tumor Cell Atlas Colin et al. EquipePM 2021-02-07
Interest of extracellular vesicles in regards to lipid nanoparticle based systems for intracellular protein delivery Le Saux et al. EquipePM 2021-06-16
Development of Amino Acids Functionalized SBA-15 for the Improvement of Protein Adsorption Gutiérrez-Climente et al. PlateformePP2I 2021-10-08
Antibody Identification for Antigen Detection in Formalin-Fixed Paraffin-Embedded Tissue Using Phage Display and Naïve Libraries Mairaville and Martineau EquipePM 2021-01-14
Anti-Müllerian hormone concentration regulates activin receptor-like kinase-2/3 expression levels with opposing effects on ovarian cancer cell survival Chauvin et al. EquipeCG 2021-07
Anti-Müllerian hormone (AMH) autocrine signaling promotes survival and proliferation of ovarian cancer cells Chauvin et al. EquipeCTCS 2021-01-26
[Strategies of tumor-pecific targeting based on the antigenic tumor specificities and the tumor microenvironment characteristics] Mangeat et al. EquipePM 2020-10
Biasing human epidermal growth factor receptor 4 (HER4) tyrosine kinase signaling with antibodies: Induction of cell death by antibody-dependent HER4 intracellular domain trafficking Lanotte et al. EquipePM Jul 2020
[Players from the program "Investments for the Future": MAbImprove MabEx] Larivière et al. EquipeAP Dec 2019
Targets for MAbs: innovative approaches for their discovery & validation, LabEx MAbImprove 6th antibody industrial symposium, June 25-26, 2018, Montpellier, France Martineau et al. EquipeAT May 01, 2019
Targeting Aspergillus fumigatus Crf Transglycosylases With Neutralizing Antibody Is Relevant but Not Sufficient to Erase Fungal Burden in a Neutropenic Rat Model Chauvin et al. PlateformePP2I 2019
Les formats alternatifs aux anticorps: Fragments et nouvelles charpentes Kitten and Martineau EquipePM 12/2019
Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related (ATR) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer Combès et al. EquipeNB 06 01, 2019
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37 Items


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Located in the Parc Euromédecine, the Institut de Recherche en Cancérologie de Montpellier (U1194) is located on the Val d'Aurelle Campus (ICM, Institut régional du Cancer Montpellier/ Val d'Aurelle).

U1194 Research Centre supported by Inserm, the University of Montpellier and the Institut du Cancer de Montpellier (ICM)

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