Research
Epitranscriptomics & Cancer Adaptation : A.David

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Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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15 Items
Title  Creator  Group name  Publishing year 
Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma Herviou et al. EquipeEJ 12/2021
The mouse HP1 proteins are essential for preventing liver tumorigenesis Saksouk et al. EquipeAM 2020-03
Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing Shoaib et al. EquipeEJ Sep 12, 2018
Cell-cycle regulation of non-enzymatic functions of the Drosophila methyltransferase PR-Set7 Zouaz et al. EquipeEJ Apr 06, 2018
Histone H4K20 tri-methylation at late-firing origins ensures timely heterochromatin replication Brustel et al. EquipeCTCS 09 15, 2017
Structures of Nahuoic Acids B-E Produced in Culture by a Streptomyces sp. Isolated from a Marine Sediment and Evidence for the Inhibition of the Histone Methyl Transferase SETD8 in Human Cancer Cells by Nahuoic Acid A Williams et al. EquipeEJ Feb 19, 2016
The transcription factor E4F1 coordinates CHK1-dependent checkpoint and mitochondrial functions Rodier et al. EquipeEJ Apr 14, 2015
Coupling mitosis to DNA replication: the emerging role of the histone H4-lysine 20 methyltransferase PR-Set7 Brustel et al. EquipeEJ Aug 2011
The histone H4 Lys 20 methyltransferase PR-Set7 regulates replication origins in mammalian cells Tardat et al. EquipeEJ Nov 2010
PR-SET7 and SUV4-20H regulate H4 lysine-20 methylation at imprinting control regions in the mouse Pannetier et al. EquipeEJ Oct 2008
PR-Set7-dependent lysine methylation ensures genome replication and stability through S phase Tardat et al. EquipeEJ Dec 31, 2007
Epigenetic regulation of histone H3 serine 10 phosphorylation status by HCF-1 proteins in C. elegans and mammalian cells Lee et al. EquipeEJ Nov 28, 2007
E4F1 is an atypical ubiquitin ligase that modulates p53 effector functions independently of degradation Le Cam et al. EquipeEJ Nov 17, 2006
Anti-HPA-9bw (Maxa) fetomaternal alloimmunization, a clinically severe neonatal thrombocytopenia: difficulties in diagnosis and therapy and report on eight families Kaplan et al. EquipeEJ Nov 2005
A switch in mitotic histone H4 lysine 20 methylation status is linked to M phase defects upon loss of HCF-1 Julien and Herr EquipeEJ Jun 18, 2004
15 Items


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Located in the Parc Euromédecine, the Institut de Recherche en Cancérologie de Montpellier (U1194) is located on the Val d'Aurelle Campus (ICM, Institut régional du Cancer Montpellier/ Val d'Aurelle).

U1194 Research Centre supported by Inserm, the University of Montpellier and the Institut du Cancer de Montpellier (ICM)

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Institut de Recherche en Cancérologie de
Montpellier (U1194) - Campus Val d'Aurelle

208 avenue des Apothicaires
34298 Montpellier cedex 5 FRANCE

 

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© Institut de Recherche en Cancérologie de Montpellier - 2011 - Tous droits réservés - Mentions légales - Connexion - Conception : ID Alizés