Research
Epitranscriptomics & Cancer Adaptation : A.David

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Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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20 Items
Title  Creator  Group name  Publishing year 
E4F1 coordinates pyruvate metabolism and the activity of the elongator complex to ensure translation fidelity during brain development Di Michele et al. EquipeCTCS 2025-01-02
Identification of monoclonal antibodies from naive antibody phage-display libraries for protein detection in formalin-fixed paraffin-embedded tissues Mairaville et al. EquipePM 2024-07-25
Design and selection of optimal ErbB-targeting bispecific antibodies in pancreatic cancer Rabia et al. EquipeJC 2023
In high-grade ovarian carcinoma, platinum-sensitive tumor recurrence and acquired-resistance derive from quiescent residual cancer cells that overexpress CRYAB, CEACAM6, and SOX2 du Manoir et al. EquipeCTCS 2022-07
A 31-plex panel for high-dimensional single-cell analysis of murine preclinical models of solid tumors by imaging mass cytometry Glasson et al. EquipeNB 2022
The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes Lacroix et al. EquipeLLC 2021-12-02
Anti-tumoral activity of the Pan-HER (Sym013) antibody mixture in gemcitabine-resistant pancreatic cancer models Rabia et al. EquipeCG 2021 Jan-Dec
The mouse HP1 proteins are essential for preventing liver tumorigenesis Saksouk et al. EquipeAM 2020-03
Notch inhibition overcomes resistance to tyrosine kinase inhibitors in EGFR-driven lung adenocarcinoma Bousquet Mur et al. EquipeAM 2020-02-03
Immunotherapy of triple-negative breast cancer with cathepsin D-targeting antibodies Ashraf et al. EquipeAT Feb 04, 2019
The mouse HP1 proteins are not required for cell viability but are essential for preventing liver tumorigenesis Saksouk et al. EQUIPEFC janvier 1, 2018
Targeting the NRG1/HER3 pathway in tumor cells and cancer-associated fibroblasts with an anti-neuregulin 1 antibody inhibits tumor growth in pre-clinical models of pancreatic cancer Ogier et al. EquipeAP 09 28, 2018
Checkpoint kinase 1 inhibition sensitises transformed cells to dihydroorotate dehydrogenase inhibition Arnould et al. PlateformeRHEM 2017-11-10
E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis Goguet-Rubio et al. EquipeLL 09 27, 2016
Antifibrotic, Antioxidant, and Immunomodulatory Effects of Mesenchymal Stem Cells in HOCl-Induced Systemic Sclerosis Maria et al. EquipeELC Apr 2016
Can Peto's paradox be used as the null hypothesis to identify the role of evolution in natural resistance to cancer? A critical review Ducasse et al. PlateformeRHEM 12/2015
Lung endothelial barrier disruption in Lyl1-deficient mice Pirot et al. PlateformeRHEM Apr 15, 2014
BAT3 modulates p300-dependent acetylation of p53 and autophagy-related protein 7 (ATG7) during autophagy Sebti et al. PlateformeRHEM Mar 18, 2014
BAG6/BAT3 modulates autophagy by affecting EP300/p300 intracellular localization Sebti et al. EquipeELC Jul 2014
?-Arrestin2 plays a key role in the modulation of the pancreatic beta cell mass in mice Ravier et al. PlateformeRHEM 3/2014
20 Items


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Located in the Parc Euromédecine, the Institut de Recherche en Cancérologie de Montpellier (U1194) is located on the Val d'Aurelle Campus (ICM, Institut régional du Cancer Montpellier/ Val d'Aurelle).

U1194 Research Centre supported by Inserm, the University of Montpellier and the Institut du Cancer de Montpellier (ICM)

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