Research
Epitranscriptomics & Cancer Adaptation : A.David

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Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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11 Items
Title  Creator  Group name  Publishing year 
Multi-Level Control of the ATM/ATR-CHK1 Axis by the Transcription Factor E4F1 in Triple-Negative Breast Cancer Batnini et al. EquipeCTCS 2022-08-16
In high-grade ovarian carcinoma, platinum-sensitive tumor recurrence and acquired-resistance derive from quiescent residual cancer cells that overexpress CRYAB, CEACAM6, and SOX2 du Manoir et al. EquipeCTCS 2022-07
Anti-tumoral activity of the Pan-HER (Sym013) antibody mixture in gemcitabine-resistant pancreatic cancer models Rabia et al. EquipeCG 2021 Jan-Dec
Targeting MDM2-dependent serine metabolism as a therapeutic strategy for liposarcoma Cissé et al. EquipeLLC 2020-06-10
Coprs inactivation leads to a derepression of LINE1 transposons in spermatocytes Paul et al. EquipeAM Jan 2019
An auristatin-based antibody-drug conjugate targeting HER3 enhances the radiation response in pancreatic cancer Bourillon et al. EquipeELC 2019-10-01
Checkpoint kinase 1 inhibition sensitises transformed cells to dihydroorotate dehydrogenase inhibition Arnould et al. PlateformeRHEM 2017-11-10
E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis Goguet-Rubio et al. EquipeLL 09 27, 2016
E4F1 controls a transcriptional program essential for pyruvate dehydrogenase activity Lacroix et al. EquipeCTCS 09 27, 2016
The transcription factor E4F1 coordinates CHK1-dependent checkpoint and mitochondrial functions Rodier et al. EquipeEJ Apr 14, 2015
Lung endothelial barrier disruption in Lyl1-deficient mice Pirot et al. PlateformeRHEM Apr 15, 2014
11 Items


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Located in the Parc Euromédecine, the Institut de Recherche en Cancérologie de Montpellier (U1194) is located on the Val d'Aurelle Campus (ICM, Institut régional du Cancer Montpellier/ Val d'Aurelle).

U1194 Research Centre supported by Inserm, the University of Montpellier and the Institut du Cancer de Montpellier (ICM)

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