Research
Epitranscriptomics & Cancer Adaptation : A.David

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Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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11 Items
Title  Creator  Group name  Publishing year 
E4F1 coordinates pyruvate metabolism and the activity of the elongator complex to ensure translation fidelity during brain development Di Michele et al. EquipeCTCS 2025-01-02
Multi-Level Control of the ATM/ATR-CHK1 Axis by the Transcription Factor E4F1 in Triple-Negative Breast Cancer Batnini et al. EquipeCTCS 2022-08-16
Computational Model of Heterogeneity in Melanoma: Designing Therapies and Predicting Outcomes Hodgkinson et al. EquipeLLC 2022
The p53 Pathway and Metabolism: The Tree That Hides the Forest Lahalle et al. EquipeLLC 2021-01-04
The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes Lacroix et al. EquipeLLC 2021-12-02
SingleCellSignalR: inference of intercellular networks from single-cell transcriptomics Cabello-Aguilar et al. EquipeJC Mar 20, 2020
Metabolic functions of the tumor suppressor p53: Implications in normal physiology, metabolic disorders, and cancer Lacroix et al. EquipeLLC 2020-03
E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis Goguet-Rubio et al. EquipeLL 09 27, 2016
E4F1 controls a transcriptional program essential for pyruvate dehydrogenase activity Lacroix et al. EquipeCTCS 09 27, 2016
The transcription factor E4F1 coordinates CHK1-dependent checkpoint and mitochondrial functions Rodier et al. EquipeEJ Apr 14, 2015
E4F1 is an atypical ubiquitin ligase that modulates p53 effector functions independently of degradation Le Cam et al. EquipeEJ Nov 17, 2006
11 Items


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Located in the Parc Euromédecine, the Institut de Recherche en Cancérologie de Montpellier (U1194) is located on the Val d'Aurelle Campus (ICM, Institut régional du Cancer Montpellier/ Val d'Aurelle).

U1194 Research Centre supported by Inserm, the University of Montpellier and the Institut du Cancer de Montpellier (ICM)

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Montpellier (U1194) - Campus Val d'Aurelle

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