Research
Epitranscriptomics & Cancer Adaptation : A.David

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Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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10 Items
Title  Creator  Group name  Publishing year 
E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis Goguet-Rubio et al. EquipeLLC Sep 27 2016
E4F1 controls a transcriptional program essential for pyruvate dehydrogenase activity Lacroix et al. EquipeLLC Sep 27 2016
The transcription factor E4F1 coordinates CHK1-dependent checkpoint and mitochondrial functions Rodier et al. EquipeCTCS Apr 14 2015
Description of an optimized ChIP-seq analysis pipeline dedicated to genome wide identification of E4F1 binding sites in primary and transformed MEFs Houles et al. EquipeLLC Sep 2015
Leukoencephalopathy with cysts and hyperglycinemia may result from NFU1 deficiency Nizon et al. EquipeCTCS Mar 2014
E4F1 deficiency results in oxidative stress-mediated cell death of leukemic cells Hatchi et al. EquipeLLC Jul 4 2011
E4F1 connects the Bmi1-ARF-p53 pathway to epidermal stem cell-dependent skin homeostasis Caramel et al. EquipeLLC Mar 15 2011
Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis Lacroix et al. EquipeLLC Dec 7 2010
The histone-binding protein COPR5 is required for nuclear functions of the protein arginine methyltransferase PRMT5 Lacroix et al. EquipeLLC May 2008
The LIM-only protein FHL2 is a negative regulator of E4F1 Paul et al. EquipeEJ Sep 07, 2006
10 Items


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Located in the Parc Euromédecine, the Institut de Recherche en Cancérologie de Montpellier (U1194) is located on the Val d'Aurelle Campus (ICM, Institut régional du Cancer Montpellier/ Val d'Aurelle).

U1194 Research Centre supported by Inserm, the University of Montpellier and the Institut du Cancer de Montpellier (ICM)

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Montpellier (U1194) - Campus Val d'Aurelle

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34298 Montpellier cedex 5 FRANCE

 

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