Research
Epitranscriptomics & Cancer Adaptation : A.David

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Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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14 Items
Title  Creator  Group name  Publishing year 
Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia Boutzen et al. EquipeLLC Apr 4 2016
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Klionsky et al. EquipeCG Jan 2 2016
E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis Goguet-Rubio et al. EquipeLLC Sep 27 2016
E4F1 controls a transcriptional program essential for pyruvate dehydrogenase activity Lacroix et al. EquipeLLC Sep 27 2016
Chromatin-Bound MDM2 Regulates Serine Metabolism and Redox Homeostasis Independently of p53 Riscal et al. EquipeLLC May 31 2016
The transcription factor E4F1 coordinates CHK1-dependent checkpoint and mitochondrial functions Rodier et al. EquipeCTCS Apr 14 2015
Numb is required to prevent p53-dependent senescence following skeletal muscle injury Le Roux et al. EquipeLLC 2015
Description of an optimized ChIP-seq analysis pipeline dedicated to genome wide identification of E4F1 binding sites in primary and transformed MEFs Houles et al. EquipeLLC Sep 2015
[Role of the p53 tumor suppressor in metabolism] Lacroix et al. EquipeLLC Dec 2013
[The Yin and the Yang of senescence: is it possible to age without developing cancer?] Lacroix et al. EquipeLLC Mar 2012
E4F1 deficiency results in oxidative stress-mediated cell death of leukemic cells Hatchi et al. EquipeLLC Jul 4 2011
E4F1 connects the Bmi1-ARF-p53 pathway to epidermal stem cell-dependent skin homeostasis Caramel et al. EquipeLLC Mar 15 2011
Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis Lacroix et al. EquipeLLC Dec 7 2010
The LIM-only protein FHL2 is a negative regulator of E4F1 Paul et al. EquipeEJ Sep 07, 2006
14 Items


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Located in the Parc Euromédecine, the Institut de Recherche en Cancérologie de Montpellier (U1194) is located on the Val d'Aurelle Campus (ICM, Institut régional du Cancer Montpellier/ Val d'Aurelle).

U1194 Research Centre supported by Inserm, the University of Montpellier and the Institut du Cancer de Montpellier (ICM)

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Montpellier (U1194) - Campus Val d'Aurelle

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© Institut de Recherche en Cancérologie de Montpellier - 2011 - Tous droits réservés - Mentions légales - Connexion - Conception : ID Alizés