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Epitranscriptomics & Cancer Adaptation : A.David

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Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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14 Items
Title  Creator  Group name  Publishing year 
E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis Goguet-Rubio et al. EquipeLLC Sep 27 2016
E4F1 controls a transcriptional program essential for pyruvate dehydrogenase activity Lacroix et al. EquipeLLC Sep 27 2016
The transcription factor E4F1 coordinates CHK1-dependent checkpoint and mitochondrial functions Rodier et al. EquipeCTCS Apr 14 2015
AMPK/HuR-Driven IL-20 Post-Transcriptional Regulation in Psoriatic Skin Garcin et al. EquipeLLC Jun 15 2015
[Role of the p53 tumor suppressor in metabolism] Lacroix et al. EquipeLLC Dec 2013
[The Yin and the Yang of senescence: is it possible to age without developing cancer?] Lacroix et al. EquipeLLC Mar 2012
Clinical expression and new SPINK5 splicing defects in Netherton syndrome: unmasking a frequent founder synonymous mutation and unconventional intronic mutations Lacroix et al. EquipeLLC Mar 2012
E4F1 deficiency results in oxidative stress-mediated cell death of leukemic cells Hatchi et al. EquipeLLC Jul 4 2011
E4F1 connects the Bmi1-ARF-p53 pathway to epidermal stem cell-dependent skin homeostasis Caramel et al. EquipeLLC Mar 15 2011
[Elastase 2, a key player in the integrity of the epidermal barrier and in Netherton syndrome] Bonnart et al. EquipeLLC Aug-Sep 2010
Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis Lacroix et al. EquipeLLC Dec 7 2010
Par2 inactivation inhibits early production of TSLP, but not cutaneous inflammation, in Netherton syndrome adult mouse model Briot et al. EquipeLLC Dec 2010
The histone-binding protein COPR5 is required for nuclear functions of the protein arginine methyltransferase PRMT5 Lacroix et al. EquipeLLC May 2008
The LIM-only protein FHL2 is a negative regulator of E4F1 Paul et al. EquipeEJ Sep 07, 2006
14 Items


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Located in the Parc Euromédecine, the Institut de Recherche en Cancérologie de Montpellier (U1194) is located on the Val d'Aurelle Campus (ICM, Institut régional du Cancer Montpellier/ Val d'Aurelle).

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