Research
Epitranscriptomics & Cancer Adaptation : A.David

Activities

Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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Title  Creator  Group name  Publishing year 
Prediction of response to promising first-line chemotherapy in ovarian cancer patients with residual peritoneal tumors: practical biomarkers and robust multiplex models Kawabata-Iwakawa et al. EquipeJC 2024-09
Modeling the Simultaneous Dynamics of Proteins in Blood Plasma and the Cerebrospinal Fluid in Human In Vivo Giroux et al. EquipeJC 2024-07-05
Farnesyltransferase inhibition overcomes oncogene-addicted non-small cell lung cancer adaptive resistance to targeted therapies Figarol et al. EquipeJC 2024-06-27
Enabling population protein dynamics through Bayesian modeling Lehmann et al. EquipeJC 2024-08-02
Cancer-associated fibroblast spatial heterogeneity and EMILIN1 expression in the tumor microenvironment modulate TGF-? activity and CD8+ T-cell infiltration in breast cancer Honda et al. EquipeJC 2024
ATR inhibition potentiates FOLFIRINOX cytotoxic effect in models of pancreatic ductal adenocarcinoma by remodelling the tumour microenvironment Bruciamacchie et al. EquipeCG 2024-11-29
Modular response analysis reformulated as a multilinear regression problem Borg et al. EquipeJC 2023-04-06
Inferring ligand-receptor cellular networks from bulk and spatial transcriptomic datasets with BulkSignalR Villemin et al. EquipeMY 2023-05-05
FT-GPI, a highly sensitive and accurate predictor of GPI-anchored proteins, reveals the composition and evolution of the GPI proteome in Plasmodium species Sauer et al. EquipeJC 2023-01-25
Design and selection of optimal ErbB-targeting bispecific antibodies in pancreatic cancer Rabia et al. EquipeJC 2023
Circulating DNA reveals a specific and higher fragmentation of the Y chromosome Thierry et al. EquipeMY 2023-11
The landscape of cancer-associated fibroblasts in colorectal cancer liver metastases Giguelay et al. EquipePM 2022
Mechanisms underlying the cooperation between loss of epithelial polarity and Notch signaling during neoplastic growth in Drosophila Logeay et al. EquipeJC 2022-02-01
Mechanical signatures of human colon cancers Lopez-Crapez et al. EquipeJC 2022-07-21
Detection of soluble biomarkers of pancreatic cancer in endoscopic ultrasound-guided fine-needle aspiration samples Souche et al. EquipeJC 2022-05
Application of modular response analysis to medium- to large-size biological systems Mekedem et al. EquipeJC 2022-04
Transcriptomic and genomic heterogeneity in blastic plasmacytoid dendritic cell neoplasms: from ontogeny to oncogenesis Renosi et al. EquipeJC 2021-03-09
The immune contexture of primary central nervous system diffuse large B cell lymphoma associates with patient survival and specific cell signaling Alame et al. EquipeJC 2021
MAGI1 inhibits the AMOTL2/p38 stress pathway and prevents luminal breast tumorigenesis Kantar et al. EquipeAM 12/2021
An R package for generic modular response analysis and its application to estrogen and retinoic acid receptor crosstalk Jimenez-Dominguez et al. EquipeJC 2021-03-31
The molecular landscape and microenvironment of salivary duct carcinoma reveal new therapeutic opportunities Alame et al. EquipeJC 2020-03-15
SingleCellSignalR: inference of intercellular networks from single-cell transcriptomics Cabello-Aguilar et al. EquipeJC Mar 20, 2020
Notch inhibition overcomes resistance to tyrosine kinase inhibitors in EGFR-driven lung adenocarcinoma Bousquet Mur et al. EquipeAM 2020-02-03
Machine Learning-Assisted Evaluation of Circulating DNA Quantitative Analysis for Cancer Screening Tanos et al. EquipeCTCS 2020-09
The Prognostic Impact of the Aryl Hydrocarbon Receptor (AhR) in Primary Breast Cancer Depends on the Lymph Node Status Jeschke et al. EquipeVC Feb 26, 2019


© Institut de Recherche en Cancérologie de Montpellier - 2011 - Tous droits réservés - Mentions légales - Connexion - Conception : ID Alizés